Results 121 to 130 of about 1,781,268 (316)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Productivity Growth and Biased Technological Change in Hydroelectric Generating Dams [PDF]

open access: yes
This paper analyses productivity growth and the nature of techni- cal change in a sample of Portuguese hydroelectric generating plants over the period 2001 to 2004.
Walter Briec   +2 more
core  

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

GIST -- Generating InStructional Text -- Requirements and Architecture Specification

open access: yes, 1994
This report is based on meetings with technical writers and translators in Italy and Britain. The objective of these meetings was to understand how pensions-related forms and their accompanying texts are currently produced and translated by our user ...
Generating Instructional
core  

Algorithm for Generating Text Descriptions of Bit Calendars

open access: yes, 2009
The article deals with the problematics of generating calendar text descriptions based on their bit map. We introduce the description of the algorithm we have designed, its basic ideas and parts.
Hynek Bachraty, Emil Krsak, Marek Tavac
core   +1 more source

Statistics in Weak Ascent Sequences

open access: yesMathematics
Weak ascent sequences are a generalization of ascent sequences that appear in many combinatorial problems. In this paper, we give a method to find generating functions that count how often a given statistic τ appears in weak ascent sequences of length n,
Toufik Mansour
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Linearity-Generating Processes: A Modelling Tool Yielding Closed Forms for Asset Prices [PDF]

open access: yes
This methodological paper presents a class of stochastic processes with appealing properties for theoretical or empirical work in finance and macroeconomics, the "linearity-generating" class.
Xavier Gabaix
core  

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