Results 111 to 120 of about 764,748 (296)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

On a class of polynomials associated with the paths in a graph and its application to minimum nodes disjoint path coverings of graphs

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1983
Let G be a graph. With every path α of G let us associate a weight wα With every spanning subgraph C of G consisting of paths α1,α2,…,αk, let us associate the weight w(C)=∏i=1kwαi.
E. J. Farrell
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

The total number of descents and levels in (cyclic) tensor words [PDF]

open access: yesDiscrete Mathematics Letters
Sela Fried, Toufik Mansour
doaj   +1 more source

Generating functions for monomial characters of wreath products ℤ/dℤ≀ 𝕾_n [PDF]

open access: yesEnumerative Combinatorics and Applications, 2021
Mark Skandera
doaj  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

A Generating Function for Fatgraphs

open access: yes, 1992
24 pages, uses harvmac macro, 1 figure not included, Saclay preprint SPhT/92 ...
Di Francesco, P., Itzykson, C.
openaire   +3 more sources

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