Results 111 to 120 of about 19,306,633 (313)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A New Generating Function for Hermite Polynomials

open access: yesInternational Journal of Mathematics and Mathematical Sciences
This paper presents a new generating function of the form gx,t=∑n=0∞tnHnex for Hermite polynomials and reveals its connection with the incomplete gamma function.
Manouchehr Amiri
doaj   +1 more source

Estimating Generating Functions

open access: yesThe Annals of Statistics, 1975
This note shows that, under appropriate conditions, if a function $A(\theta; t)$ of an unknown parameter $\theta$ and a real variable $t$ has an infinite series expansion and if there is a function $B(S; t)$ of the sufficient statistic $S$ which is an unbiased estimator of $A$ for every $t$ and which also has an infinite series expansion, then the ...
openaire   +3 more sources

Hypergeometric Generating Function of L-function, Slater's Identities, and Quantum Invariant

open access: yes, 2004
We study certain connections between the quantum invariants of the torus knots T_{3,2^k} and some q-series identities.
Anatol, Kazuhiro Hikami, N. Kirillov
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

SOME BILINEAR GENERATING FUNCTIONS [PDF]

open access: yesProceedings of the National Academy of Sciences, 1969
In the present paper, the author applies some of his earlier results which extend the well-known Hille-Hardy formula for the Laguerre polynomials to certain classes of generalized hypergeometric polynomials in order to derive various generalizations of a bilinear generating function for the Jacobi polynomials proved recently by Carlitz.
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Solving arbitrary one-loop reduction via generating function

open access: yesEuropean Physical Journal C: Particles and Fields
Recently, the concept of generating function has been employed in one-loop reduction. For one-loop integrals encompassing arbitrary tensor ranks and higher-pole contributions, the generating function can be decomposed into a tensor part and a higher-pole
Tingfei Li, Yuekai Song, Liang Zhang
doaj   +1 more source

Home - About - Disclaimer - Privacy