Results 111 to 120 of about 9,477,739 (271)

An Innovative Approach for Forecasting Hydroelectricity Generation by Benchmarking Tree-Based Machine Learning Models

open access: yesApplied Sciences
Hydroelectricity, one of the oldest and most potent forms of renewable energy, not only provides low-cost electricity for the grid but also preserves nature through flood control and irrigation support.
Bektaş Aykut Atalay, Kasım Zor
doaj   +1 more source

Third-Generation TB-LMTO

open access: yes, 1998
We describe the screened Korringa-Kohn-Rostoker (KKR) method and the third-generation linear muffin-tin orbital (LMTO) method for solving the single-particle Schroedinger equation for a MT potential.
Andersen, O. K.   +6 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Statistical research development of neural networks and their role in the field of video production

open access: yesСовременная наука и инновации
The development of technology these days is amazing in its rapidity. Computer and network technologies have come a long way from local file sharing services to a global repository that absorbs the knowledge of many generations of humanity. However, now a
A. A. Kostoglotov   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Children of the Revolution, the Nation’s Future: Understanding the Multigenerational Audience of the Rock in Rio Music Festival

open access: yesInternational Journal of Communication, 2020
This article presents the results of a two-year research project on the Brazilian music festival Rock in Rio. The research consists of an analysis of the particular circumstances that led to the formation of the festival’s multigenerational audience ...
Juliana Müller
doaj  

Home - About - Disclaimer - Privacy