Results 41 to 50 of about 2,788,102 (267)

Application of the target trial emulation framework to external comparator studies

open access: yesFrontiers in Drug Safety and Regulation
External comparator (EC) studies are increasingly being used to generate evidence that supports the evaluation of emerging pharmacological treatments for regulatory and health technology assessment (HTA) purposes.
Kellyn Arnold   +3 more
doaj   +1 more source

GENERALIZED SPACES OF GENERAL RELATIVITY [PDF]

open access: yesProceedings of the National Academy of Sciences, 1959
1. This paper is a revision of the paper with the same title which was published a year ago. The paper deals with a space of four dimensions V4 of coordinates xi as i takes the values 1 to 4. The geometry of the space is based upon the asymmetric functions gij and the asymmetric coefficients of connection Prk and upon the Einsteinm equation2 gij,k ...
openaire   +2 more sources

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall   +2 more
wiley   +1 more source

Effectiveness and safety of bedaquiline, pretomanid, linezolid and moxifloxacin in drug-resistant tuberculosis patients in selected public hospitals in Ethiopia: a multicenter retrospective cohort study

open access: yesBMC Infectious Diseases
Introduction Tuberculosis is a major public health problem, and its treatment has become challenging due to the emergence of drug-resistant tuberculosis.
Bisrat Solomon   +13 more
doaj   +1 more source

Design of radiation hardened based on the high performance RISC-V processor

open access: yesDianzi Jishu Yingyong
With the rapid development of space technology, the reliability of chips in the irradiation environment becomes more and more prominent. In this paper, based on the RISC-V architecture high-performance processor C501, the triple modular redundancy and ...
Huang Qiang   +3 more
doaj   +1 more source

High-throughput Quant-iT PicoGreen assay using an automated liquid handling system

open access: yesBioTechniques, 2019
Workflows in NGS facilities require high-standard practices and high-throughput pipelines to process the large number of samples received in a timely manner. Downstream protocols such as NGS library preparation require accurate estimation of nucleic acid
Kay Anantanawat   +3 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo   +5 more
wiley   +1 more source

Generation of weather windows to develop agro advisories for Tamil Nadu under automated weather forecast system

open access: yesJournal of Agrometeorology, 2022
With the objective of providing weather windows at block level of Tamil Nadu for developing agro advisories in respect of dominant crops, an exploratory research was conducted with four levels of rainfall, three levels of maximum temperature, three ...
T. N. BALASUBRAMANIAN   +4 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge   +6 more
wiley   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa   +7 more
wiley   +1 more source

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