Results 61 to 70 of about 14,221,676 (384)

Application of the target trial emulation framework to external comparator studies

Frontiers in Drug Safety and Regulation
External comparator (EC) studies are increasingly being used to generate evidence that supports the evaluation of emerging pharmacological treatments for regulatory and health technology assessment (HTA) purposes.
Kellyn Arnold, Luis Antunes, Briana Coles, Hopin Lee   +3 more
doaj   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Generation of weather windows to develop agro advisories for Tamil Nadu under automated weather forecast system

Journal of Agrometeorology, 2022
With the objective of providing weather windows at block level of Tamil Nadu for developing agro advisories in respect of dominant crops, an exploratory research was conducted with four levels of rainfall, three levels of maximum temperature, three ...
T. N. BALASUBRAMANIAN, R. JAGANNATHAN, N. MARAGATHAM, K. SATHYAMOORTHI, R. NAGARAJAN   +4 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source

MKtree: generation and simulations [PDF]

, 2002
The problem to represent very complex systems has been studied by several authors, obtaining solutions based on different data structures. In this paper, a K dimensional tree (Multirresolution Kdtree, MKtree) is introduced.
Brunet Crosa, Pere, Franquesa Niubó, Marta   +1 more
core   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel, Patricia Pastura, Joshua P. Scallan, Timothy D. Le Cras   +3 more
wiley   +1 more source

Impact of KOH Wet Treatment on the Electrical and Optical Characteristics of GaN-Based Red μLEDs

Crystals
Micro-size light-emitting diodes (μLEDs) are high-brightness, low-power optoelectronic devices with significant potential in display technology, lighting, and biomedical applications.
Shuhan Zhang, Yun Zhang, Hongyu Qin, Qian Fan, Xianfeng Ni, Li Tao, Xing Gu   +6 more
doaj   +1 more source

The modern labour market in Poland and the generation. The differences between generations X, Y and Z.

Rozprawy Społeczne, 2020
The contemporary labour market in Poland is undergoing constant transformations, which result from demographic changes, mainly related to the process of population ageing.
Karolina Martyna Czyczerska, Anna Jadwiga Ławnik, Elżbieta Szlenk-Czyczerska   +2 more
doaj   +1 more source

Next Generation Learning [PDF]

, 2010
Describes the foundation's investments in utilizing technology to develop innovative learning models and personalized educational pathways to help low-income and minority high school students graduate ready for college and obtain postsecondary ...

core