Results 71 to 80 of about 9,477,739 (271)
Status of dynamical ensemble generation
I give an overview of current and future plans of dynamical QCD ensemble generation activities. A comparison of simulation cost between different discretizations is made. Recent developments in techniques and algorithms used in QCD dynamical simulations,
Jung, Chulwoo
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Quantum random number generation
Quantum physics can be exploited to generate true random numbers, which play important roles in many applications, especially in cryptography. Genuine randomness from the measurement of a quantum system reveals the inherent nature of quantumness ...
Cao, Zhu +4 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Adversarial Generation of Natural Language
Generative Adversarial Networks (GANs) have gathered a lot of attention from the computer vision community, yielding impressive results for image generation.
Courville, Aaron +4 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Fatigue prediction of high-strength bolts in wind turbines
The flange plate and blade root hub of wind turbines are connected by high-strength bolts, and the collapse of most wind turbine towers is caused by the fatigue of the connecting bolts.
Zheng Qishan +5 more
doaj +1 more source
Background The diet impact on cardiovascular diseases has been investigated widely, but the association between dietary patterns (DPs) and subclinical cardiovascular damage remains unclear.
Sandra Wagner +14 more
doaj +1 more source
The Reichssicherheitshauptamt (RSHA) was once the capital of a vast empire of terror; a place where surveillance, persecution, and extermination became merely a quotidian, bureaucratic function and where the Schreibtischtäter could implement their deadly
Hough, Sean W.
core

