Results 71 to 80 of about 495,921 (307)

Random number generation and working memory. [PDF]

open access: yes, 2007
We demonstrate the close relationship that exists between random sequence generation and working memory functioning. We clarify the nature of this link by examining the impact of concurrent requirements for random sequence response quality.
Towse, John N., Cheshire, Andrea
core  

Conservation and genetic analysis of the endangered Martina Franca donkey using pedigree data

open access: yesFrontiers in Animal Science
IntroductionThe Martina Franca donkey is an endangered Italian breed with historical significance in agriculture and therapy. Conservation efforts are crucial due to increasing risks of genetic erosion and inbreeding.MethodsPedigree data from 2,261 ...
Claudia Pierini   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Genetic gain, increase in inbreeding rate and generation interval in alternatives of Pinzgau breeding program

open access: yesCzech Journal of Animal Science, 2004
The aim of this paper was to analyse alternatives of Pinzgau breeding program. Alternatives were optimised for genetic gain of selection index composed of parameters of milk efficiency traits and increase in inbreeding per generation.
O. Kadlečík, R. Kasarda, L. Hetényi
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Interval forecasting of solar power generation

open access: yes, 2021
Solar energy is one of the most promising renewable energy sources for electricity generation due to its long lifespan and low maintenance fee.
Leong, Jia Hao
core  

Estimating effective reproduction number using generation time versus serial interval, with application to covid-19 in the Greater Toronto Area, Canada

open access: yesInfectious Disease Modelling, 2020
background. The effective reproduction number Re(t) is a critical measure of epidemic potential. Re(t) can be calculated in near real time using an incidence time series and the generation time distribution: the time between infection events in an ...
Jesse Knight, Sharmistha Mishra
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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