Results 81 to 90 of about 4,042,263 (299)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Caracterização demográfica da raça Mangalarga Marchador Demographic characterization of Mangalarga Marchador breed

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2004
Data from the Brazilian Mangalarga Marchador Breed Association, including information on 292,012 animals borned from 1949 to 2000 were used to describe population structure. Frequency tables, central tendency and variation measurements according to owner,
M.D. Costa, J.A.G. Bergmann, A.S.C Resende, G.A. Martins, M.S. Bretas   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A raça Indubrasil no Nordeste brasileiro: melhoramento e estrutura populacional The Indubrasil breed in the Brazilian Northeast: breeding and population structure

Revista Brasileira de Zootecnia, 2009
Com o intuito de fornecer subsídios para programas de melhoramento, conservação e expansão da raça Indubrasil do Nordeste brasileiro, avaliaram-se o histórico evolutivo, as estimativas de parâmetros genéticos e a estrutura populacional da raça.
Paulo Luiz Souza Carneiro, Carlos Henrique Mendes Malhado, Raimundo Martins Filho, Antonio Policarpo Souza Carneiro, Fabyano Fonseca e Silva, Robledo de Almeida Torres   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Genetic gain, increase in inbreeding rate and generation interval in alternatives of Pinzgau breeding program

Czech Journal of Animal Science, 2004
The aim of this paper was to analyse alternatives of Pinzgau breeding program. Alternatives were optimised for genetic gain of selection index composed of parameters of milk efficiency traits and increase in inbreeding per generation.
O. Kadlečík, R. Kasarda, L. Hetényi
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

An Optimization Method for Day-Ahead Generation Interval of Cascade Hydropower Adapting to Multi-Source Coordinated Scheduling Requirements

Energies
Multi-source coordinated scheduling has become the predominant operational paradigm in power systems. However, substantial differences among hydropower, thermal power, wind power, and photovoltaic sources in terms of response speed, regulation capability,
Shushan Li, Chonghao Li, Huijun Wu, Zhipeng Zhao, Huan Wang, Yongxi Kang, Chuntian Cheng, Changhong Li   +7 more
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source