Results 81 to 90 of about 482,509 (266)

Inferring the differences in incubation-period and generation-interval distributions of the Delta and Omicron variants of SARS-CoV-2. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Park SW   +11 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Generation of an Interval Metric Scale to Measure Attitude

open access: yesSAGE Open, 2014
This article discusses issues of scales in measuring attitude, demonstrates how a metric scale can be generated based on three main features, and presents results from a repeated measurement survey to verify the generated scale.
Rohana Yusoff, Roziah Mohd Janor
doaj   +1 more source

Estimation of the generation interval using pairwise relative transmission probabilities. [PDF]

open access: yesBiostatistics, 2022
Leavitt SV   +6 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Generalized Interval LU Decomposition for the Solution of Interval Linear Systems [PDF]

open access: yes, 2007
Generalized intervals (intervals whose bounds are not constrained to be increasingly ordered) extend classical intervals providing better algebraic properties. In particular, the generalized interval arithmetic is a group for addition and for multiplication of zero free intervals.
Goldsztejn, Alexandre, Chabert, Gilles
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The importance of the generation interval in investigating dynamics and control of new SARS-CoV-2 variants. [PDF]

open access: yesJ R Soc Interface, 2022
Park SW   +6 more
europepmc   +1 more source

MB-Representations of Algebras Generated by Intervals

open access: yesReal Analysis Exchange, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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