Results 251 to 260 of about 1,386,053 (319)

Frontier Language Models and Optical Character Recognition Preprocessing Against Invisible Text Injection in AI Peer Review.

JAMA Netw Open
Jarrett P, Yun P, Jamieson A, Diercks D, Courtney DM, Cao D.   +5 more
europepmc   +1 more source

LLMs for industrial databases: an agro-food production plant use case. [PDF]

Front Artif Intell
Dranca L, Donate P, Sanguesa JA, Garrido P, Torres-Sanz V, Martinez FJ.   +5 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Scaffold-Lab: Critical evaluation and ranking of protein backbone generation methods in a unified framework. [PDF]

PLoS Comput Biol
Zheng Z, Zhang B, Zhong B, Yu J, Liu K, Li Z, Zhu J, Wei T, Chen HF.   +8 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Estimating the generation time for SARS-CoV-2 transmission using United States household data, December 2021-May 2023. [PDF]

Sci Rep
Chan LYH, Morris SE, Stockwell MS, Bowman NM, Asturias E, Rao S, Lutrick K, Ellingson KD, Nguyen HQ, Maldonado Y, McLaren SH, Sano E, Biddle JE, Smith-Jeffcoat SE, Biggerstaff M, Rolfes MA, Talbot HK, Grijalva CG, Borchering RK, Mellis AM, RVTN-Sentinel Study Group.   +20 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Two decades of resurrection studies: What have we learned about contemporary evolution of plant species? [PDF]

Am J Bot
Pennington LK, Sheth SN, Franks SJ, Anderson JT, Hamann E.   +4 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source