Results 81 to 90 of about 1,386,053 (319)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Analysis of tomato agronomic traits using generation mean

African Crop Science Journal, 1970
Information on inheritance of agronomic traits and lack of tomato (Solanum lycopersicum L.) a robust breeding programme in Kenya, has led to dependency on imported tomato varieties. The objective of this study was to assess the inheritance of growth attributes of tomato lines in Kenya and identify cross family with great potential for further breeding.
Kathimba, F.K., Kimani, P.M., Narla, R.D., Kiriika , L.M.   +3 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Mean equation based scaling analysis of fully-developed turbulent channel flow with uniform heat generation

, 2017
Multi-scale analysis of the mean equation for passive scalar transport is used to investigate the asymp- totic scaling structure of fully developed turbulent channel flow subjected to uniform heat generation.
Ang Zhou, Joseph Klewicki, Klewicki, Joseph, Sergio Pirozzoli, Pirozzoli, Sergio, Zhou, Ang   +5 more
core   +1 more source

Understanding the genetic basis of resistance to maydis leaf blight and maturity-related traits in corn

Frontiers in Plant Science
Maize is one of the most versatile and commercially produced crops used for food, feed, fodder, ethanol, oil, and industrial raw materials. Maize is affected by various diseases, but among these, maydis leaf blight (MLB) is one of the most serious ...
Bhupender Kumar, Pushpendra, Santosh Kumar, Pardeep Kumar, Rakhi Singh, Shrikant Yankanchi, Debjyoti Sarkar, Chhavi Nath, Bahadur Singh Jat, Pravin Kumar Bagaria, Sumit Kumar Aggarwal, Prahlad Piyal, S. B. Singh, Sujay Rakshit, Sujay Rakshit, H. S. Jat   +15 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The regional electricity generation mix in Scotland: A portfolio selection approach [PDF]

Standalone levelised cost assessments of electricity supply options miss an important contribution that renewable and non-fossil fuel technologies can make to the electricity portfolio: that of reducing the variability of electricity costs, and their ...
Peter Mcgregor, Igor Eromenko, Kim Swales, Grant Allan   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Stochastic volatility in mean: Efficient analysis by a generalized mixture sampler

Journal of Econometrics
In this paper we consider the simulation-based Bayesian analysis of stochastic volatility in mean (SVM) models. Extending the highly efficient Markov chain Monte Carlo mixture sampler for the SV model proposed in Kim et al. (1998) and Omori et al. (2007), we develop an accurate approximation of the non-central chi-squared distribution as a mixture of ...
Daichi Hiraki, Siddhartha Chib, Yasuhiro Omori   +2 more
openaire   +2 more sources