Results 71 to 80 of about 4,925,039 (291)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Levy stable distributions via associated integral transform

, 2012
We present a method of generation of exact and explicit forms of one-sided, heavy-tailed Levy stable probability distributions g_{\alpha}(x), 0 \leq x < \infty, 0 < \alpha < 1.
Cont R., Debnath L., Ditkin V. A., Feller W., Graf U., K. A. Penson, K. Górska, Kahane J.-P., Lavrentiev M., Martynenko V. S., Olver F. W. J., Prudnikov A. P., Prudnikov A. P., Sneddon I. N., Uchaikin V. V., Woyczynski W. A.   +15 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Generalized X-ray pictures

Publicationes Mathematicae Debrecen, 1996
Summary: We generalize the definition of \(X\)-ray pictures by introducing weight functions. Then the corresponding Hammer-type problem is solved and applications are given.
openaire   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

LOCATION MATTERS: HOW RECYCLING SITE FEATURES INFLUENCE GENERATION X'S RECYCLING PRACTICES [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie
According to generational theory, Generation X is characterized by pragmatism and flexibility. Members of this cohort are individuals who have experienced a socio-economic transition, marked by major social changes that have developed their critical ...
BEJAN BRÎNDUȘA MARIANA, POP CIPRIAN MARCEL, SÎRBU GABRIELA NICOLETA   +2 more
doaj  

The “Imperceptibly Narrowing Diamond” Generation—Adaptation Strategies of the Generation X Representatives Toward Their Old Age

Qualitative Sociology Review
Population aging is becoming one of society’s priority issues. An assumption is that it is beneficial (the benefits for the individual and society are shown in the text) for people currently of working age (representatives of Generation X) to anticipate ...
Emilia Kramkowska, Alicja Korzeniecka-Bondar   +1 more
doaj   +1 more source

DOES THE GENERATION INFLUENCE DOMESTIC LEISURE TOURISM PRACTICES? THE CASE OF BULGARIA [PDF]

Geo Journal of Tourism and Geosites
The main goal of the article is to study the generations that are actively participating in the tourism market at the moment and to examine their attitudes towards domestic tourism. The analyses of the generations’ domestic leisure tourism practices in
Desislava VARADZHAKOVA, Alexander NAYDENOV   +1 more
doaj   +1 more source

Using radio emission to detect isolated and quiescent accreting black holes

, 2005
We discuss the implications of new relations between black holes' masses, X-ray luminosities and radio luminosities, as well as the properties of the next generation of radio telescopes, for the goal of finding isolated accreting black holes.
Maccarone, Thomas J.
core   +1 more source