Results 201 to 210 of about 1,106,397 (257)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A Pathogen Penalty? Associations Between Persistent Infections and Biological Aging in the US. [PDF]

J Infect Dis
Momkus J, Harris KM, Edwards JK, Yang YC, Martin CL, Aiello AE.   +5 more
europepmc   +1 more source

Fully synthetic replication of complex real biological cell clusters using a novel cluster-based 'Rosetta-Routine' computational modelling process. [PDF]

PLoS Comput Biol
Mason B, Justham L, Whitby L, Whitby A, Scott S, Nti S, Petzing J.   +6 more
europepmc   +1 more source

Sharper displays via field control. [PDF]

Light Sci Appl
Ma Y.
europepmc   +1 more source

A Nonanuclear Pd-Based Coordination Cage Featuring Ni-Chelated Porphyrin Ligand for Cancer Therapy via Combination of Chemodynamic and Photodynamic Modalities. [PDF]

Molecules
Dong ML, Ning Y, Jia YH, Zhang WH, Lu W, Mao Y.   +5 more
europepmc   +1 more source

Efficacy of Antipsychotic Augmentation Therapy in Treatment-Resistant Obsessive-Compulsive Disorder: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Shahtou A, Omara HR, Qari SA, Alqahtani RS, Alnasyan ZS, Alotaibi AE, Ali AA, Alabdulrahim JM, Naser SA, Asad N, Bagabas L, Jilani SA, Metwaly AS.   +12 more
europepmc   +1 more source

PlasmidGPT: A generative framework for plasmid analysis and generation. [PDF]

Sci Adv
Shao B, Han Z, Liang Z, Huo YX.
europepmc   +1 more source

Universal free-energy scaling of quantum efficiency controlled by acceptor end group strength in organic solar cells.

Laquai F, Karuthedath S, Liu W, Chaturvedi N, Paleti SHK, De Castro C, Hamsa A, Han J, Khan J, Kafourou P, Xu H, Firdaus Y, Sharma A, Althobaiti W, Villalva DR, Ramos N, Martin J, Heeney M, Baran D, Anthopoulos TD, Andrienko D, Gorenflot J, Luke J.   +22 more
europepmc   +1 more source