Results 51 to 60 of about 80,691 (309)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Introduction to \u3ci\u3eFaith and the Historian: Catholic Perspectives\u3c/i\u3e [PDF]

open access: yes, 2007
[Excerpt] What follows are the essays by eight historians touched by Catholicism on the meaning of that experience and its effect on their professional work.
Salvatore, Nick
core   +1 more source

Medicaid's Soaring Cost: Time to Step on the Brakes [PDF]

open access: yes, 2007
Current trends and policies imply unsustainable growth in federal Medicaid outlays. In the year 2006, federal Medicaid spending was 11.9 percent of federal general revenues and 1.5 percent of GDP.
Jagadeesh Gokhale
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Age, Period, and Cohort Differences in Work Centrality and Work Values

open access: yesSocieties, 2018
In this paper, we analyze whether work values differ between three dimensions of time (age, birth cohort, period). Using data of five waves of the World Values Survey and the European Values Study from more than forty countries and hierarchical age ...
Gábor Hajdu, Endre Sik
doaj   +1 more source

Examining the Fun Factors and Age Differences in Attitudes Toward Workplace Fun in Modern Companies [PDF]

open access: yesمدیریت دولتی, 2013
This paper aims to examine the fun concept and age differences in attitudes toward workplace fun. The authors review the literature on workplace fun and generational theory.
Asgari Asgari   +2 more
doaj   +1 more source

Cohorts, overlapping generations and consanguinity estimates

open access: yesAnnals of Human Biology, 1983
A number of problems in human population genetics involve determining the effects of non-random mating due to cultural or geographic factors, and therefore requires determination of expectations based on random mating. These expectations are usually taken to be the arithmetic mean of the contributions of all possible pairs drawn from a subpopulation of
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Towards an understanding of multi-generational higher education cohorts in gamified entrepreneurship education

open access: yesHeliyon
The increasing inclusion of gamified courses in entrepreneurship programmes in higher education have left gaps in understanding the critical essentials of the multi-generational student cohort undertaking these programmes.
Prince Derrick Dodoo, David Eshun Yawson
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

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