Results 61 to 70 of about 80,691 (309)
Dialectical Spaces in the Global Public Sphere: Media Memories across Generations [PDF]
, 2003 A decade ago, CNN and MTV emerged as new types of 'global' players, initiating and supporting a new global transnational community of 'news junkies' and music cultures from New York, to Tokyo, to Buenos Aires and Los Angeles.
Ingrid Volkmer
core
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Generational cohorts and their attitudes toward advertising
Tržište, 2013 This research is aimed at determining the attitudes with regard to advertising from the perspective of generational cohorts in Sarawak. A two-phase of study was conducted to firstly identify generational cohorts in the state and, secondly, to investigate
Ernest Cyril de Run, Hiram Ting
doaj
Pilot and Feasibility Studies, 2019 Background There is a strong interest in the concept of developmental origins of health and disease and their influence on various factors “from cradle to grave”.
Michelle L. Townsend +8 more
doaj +1 more source
Virtual epilepsy patient cohort: generation and evaluation
PLOS Computational BiologyAbstractEpilepsy is a prevalent brain disorder, characterized by sudden, abnormal brain activity, making it difficult to live with. One-third of people with epilepsy do not respond to anti-epileptic drugs. Drug-resistant epilepsy is treated with brain surgery.
Dollomaja, Borana +5 more
openaire +4 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Young and old competing for public welfare services [PDF]
Generational conflict affects the supply of public welfare services, and the rising share of elderly is seen as a threat to educational spending. We offer an analysis of spending in child care, primary and lower secondary education, and care for the ...
Jørn Rattsø, Lars-Erik Borge
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A Tradition of Giving: New Research on Giving and Volunteering Within Families [PDF]
, 2016 SummaryParents who volunteer with charitable organizations are more likely to have children who volunteer for, and give to, charitable organizations.While the philanthropic priorities of parents and their children are more closely aligned than those of ...
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source