Results 111 to 120 of about 2,042,710 (299)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
BMC GeriatricsBackground Grandchild caring has positive as well as negative impact on the grandparents’ psychological well-being and the findings are varied by culture and country.
Papai Barman, Harihar Sahoo
doaj +1 more source
Generations and Gender Survey (GGS) [PDF]
The Generations and Gender Survey (GGS) is one of the two pillars of the Generations and Gender Programme designed to improve understanding of demographic and social development and of the factors that influence these developments. This article describes
Aline Desesquelles +12 more
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Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Overlapping Generations: the First Jubilee. [PDF]
Paul Samuelson's (1958) overlapping generations model has turned 50. Seldom has so simple a model been so influential. The paper, in spite of its ripe age, still elicits wonder. Starting from the uncontroversial observation that “we live in a world where
Weil, Philippe
core
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Gender, generations, and nonfarm participation [PDF]
The authors present an empirical analysis of intergenerational links in nonfarm participation with a focus on gender effects. Using survey data from Nepal, the evidence shows that the mother exerts a strong influence on a daughter's employment choice ...
Emran, M. Shabe +2 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Intergenerational Justice Review, 2018 If you had to choose one moment in history in which to be born, and you didn’t know in advance whether you were going to be male or female, which country you were going to be from, what your status was, you’d choose right now.” This answer to his one ...
Jörg Tremmel +3 more
doaj