Results 61 to 70 of about 405,858 (264)

Functional Generative Design: An Evolutionary Approach to 3D-Printing

, 2018
Consumer-grade printers are widely available, but their ability to print complex objects is limited. Therefore, new designs need to be discovered that serve the same function, but are printable.
Chockchowwat, Supawit, Miikkulainen, Risto, Tutum, Cem C., Vouga, Etienne   +3 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Implementation of an Automated Code Checking Algorithm Based on Site Analysis

Buildings
To date, BIM has been primarily utilized in cost and schedule management, an interference check between architectural and structural models and systems based on geometric data in the process of the construction life cycle.
Seong Jeongmin, Shin Sangyun
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Leveraging BIM for Enhanced Camera Allocation Planning at Construction Job Sites: A Voxel-Based Site Coverage and Overlapping Analysis

Buildings
In the construction industry, the imperative for visual surveillance mechanisms is underscored by the need for safety monitoring, resources, and progress tracking, especially with the adoption of vision intelligence technology.
Si Van-Tien Tran, Doyeop Lee, Hai Chien Pham, Long H. Dang, Chansik Park, Ung-Kyun Lee   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Crafting Soft Wearables, with and through digital technologies

Temes de Disseny, 2019
As wearables and e-textiles enter into another hype cycle (Tomico et al. 2017), we find ourselves with the opportunity to reflect on the work done and the work remaining.
Bruna Goveia da Rocha, Kristina Andersen, Oscar Tomico   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

AI-assisted design of lightweight and strong 3D-printed wheels for electric vehicles.

PLoS ONE
The automotive industry is undergoing a transformative shift towards electric vehicles (EVs), driven by environmental concerns and technological advancements.
Timileyin Opeyemi Akande, Oluwaseyi O Alabi, Ali Rizwan, Sunday A Ajagbe, Amos O Olaleye, Mathew O Adigun   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source