Results 121 to 130 of about 22,229,619 (357)

Generative Denoising Method for Geological Images with Pseudo-Labeled Non-Matching Datasets

open access: yesApplied Sciences
Accurate prediction of oil and gas reservoirs requires precise river morphology. However, geological sedimentary images are often degraded by scattered non-structural noise from data errors or printing, which distorts river structures and complicates ...
Huan Zhang   +3 more
doaj   +1 more source

The Anatomy of Inference: Generative Models and Brain Structure

open access: yesFrontiers in Computational Neuroscience, 2018
To infer the causes of its sensations, the brain must call on a generative (predictive) model. This necessitates passing local messages between populations of neurons to update beliefs about hidden variables in the world beyond its sensory samples.
Thomas Parr, Karl J. Friston
doaj   +1 more source

Stochastic phonological grammars and acceptability

open access: yes, 1997
In foundational works of generative phonology it is claimed that subjects can reliably discriminate between possible but non-occurring words and words that could not be English.
Coleman, John, Pierrehumbert, Janet
core   +3 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Variational Tracking and Prediction with Generative Disentangled\n State-Space Models [PDF]

open access: green, 2019
Adnan Akhundov   +3 more
openalex   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

COTIC: Embracing Non-Uniformity in Event Sequence Data via Multilayer Continuous Convolution

open access: yesIEEE Access
Irregular event streams are common in domains such as finance, healthcare, and e-commerce, where the underlying data-generating processes are often highly complex and vary widely in scale. Models must adapt their temporal expressiveness while maintaining
Vladislav Zhuzhel   +11 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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