Results 151 to 160 of about 23,718 (313)

High‐Fidelity Synthetic Data Replicates Clinical Prediction Performance in a Million‐Patient Diabetes Cohort

open access: yesAdvanced Science, EarlyView.
This study generates high‐fidelity synthetic longitudinal records for a million‐patient diabetes cohort, successfully replicating clinical predictive performance. However, deeper analysis reveals algorithmic biases and trajectory inconsistencies that escape standard quality metrics. These findings challenge current validation norms, demonstrating why a
Francisco Ortuño   +5 more
wiley   +1 more source

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

open access: yesAdvanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio   +3 more
wiley   +1 more source

Loyola Generativity Scale and Generative Behavior Checklist: A Psychometric Study with Spanish LGBT+ Older Adults

open access: yesRevista de Enfermagem Referência
Background: Generativity has been associated with resilience and life satisfaction in older age, including among lesbian, gay, bisexual, and transgender (LGBT+) older adults. Objective: To examine the psychometric properties of the Loyola Generativity
Tatiana Casado   +4 more
doaj  

Towards academic generativity: working collaboratively with visual artefacts for self-study and social change

open access: yesSouth African Journal of Education, 2012
There appears to be a mounting consciousness in academia that knowledge production and the scholarly dissemination of knowledge do not necessarily lead to general well-being or improvement in society. In this article we start with ourselves by initiating
Kathleen Pithouse-Morgan   +1 more
doaj  

Simulating the temporal reference of Dutch and English Root Infinitives. [PDF]

open access: yes, 2004
Hoekstra & Hyams (1998) claim that the overwhelming majority of Dutch children’s Root Infinitives (RIs) are used to refer to modal (not realised) events, whereas in English speaking children, the temporal reference of RIs is free.
Freudenthal, D, Gobet, F, Pine, J M
core   +2 more sources

Solid Harmonic Wavelet Bispectrum for Image Analysis

open access: yesAdvanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown   +3 more
wiley   +1 more source

Black Single Fathers: Choosing to Parent Full-Time [PDF]

open access: yes, 2002
This ethnographic study uses the narratives of African American, single, full-time fathers to explore the motivations precipitating their choice to parent.
Coles, Roberta
core   +1 more source

Design of Safe and Efficient Adenine Base Editors via Protein Language Model Screening for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
ABSTRACT Base editors enable precise genome modification and have emerged as a promising therapeutic approach for correcting diseases caused by single‐nucleotide variants. While the current efficient version of adenine base editors (ABEs), such as ABE8e, exhibits exceptional efficiency for A‐to‐G conversions, their clinical translation is hindered by ...
Jiawei Yao   +12 more
wiley   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

open access: yesAdvanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng   +2 more
wiley   +1 more source

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