Results 251 to 260 of about 425,706 (317)

Superior Cluneal Nerve Entrapment: An Additional Consideration in Low Back Pain. [PDF]

J Orthop Case Rep
Muluk SY.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Flash Pulmonary Edema From Brief Loss of Biventricular Pacing During CRT-D Generator Exchange. [PDF]

JACC Case Rep
Fahed J, Ganthan RR, Al-Zakhari R, Isber R, Isber N.   +4 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Perioperative management of cardiac implantable electronic devices: a state of the art narrative review. [PDF]

J Thorac Dis
Fernando RJ, Crimi E, Puttur Rajkumar K, Marchant BE, Garner CR, Eastlack SC, Hicks MH, Royster RL.   +7 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Ultrasound-guided parasternal tunneling during intermuscular subcutaneous implantable cardioverter-defibrillator implantation is associated with lower shock impedance and more favorable implant geometry. [PDF]

Heart Rhythm
Sanchis-Gomar F, Schloss L, Perino AC, Viswanathan MN, Baykaner T, John RM, Rogers AJ, Badhwar N, Narayan SM, Wang PJ, Perez MV.   +10 more
europepmc   +1 more source

A deep generative approach to personalized super mario level design. [PDF]

Sci Rep
Baharvand D, Saeedi N, Gharehveran SS, Shirini K.   +3 more
europepmc   +1 more source