Results 81 to 90 of about 224,645 (295)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Generative AI to Generate Test Data Generators
IEEE SoftwareGenerating fake data is an essential dimension of modern software testing, as demonstrated by the number and significance of data faking libraries. Yet, developers of faking libraries cannot keep up with the wide range of data to be generated for different natural languages and domains.
Benoit Baudry +9 more
openaire +4 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Some Experimental Studies on Airjet and Solid Body Vortex Generators [PDF]
, 2002 generators (VGs) in an induction type wind tunnel. While the former comprised a convergent nozzle having an area ratio of 4, the later ones included vane and wedge type devices.
Shobhavathy, MT, Nagpurwala, QH
core
Alternative designs of high-temperature superconducting synchronous generators
, 2010 This paper discusses the different possible designs of both cored and coreless superconducting synchronous generators using high-temperature superconducting (HTS) tapes, with particular reference to demonstrators built at the University of Southampton ...
Goddard, K. F. +2 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Generic Extensions and Generic Polynomials
Journal of Symbolic Computation, 2000 In the paper under review the author proves that the existence of generic polynomials and generic extensions [in the sense of \textit{D. J. Saltman}, Adv. Math. 43, 250-283 (1982; Zbl 0484.12004)] are equivalent over an infinite field. Here one calls a monic polynomial \(P(s_1,\dots,s_m;X) \in K(s_1,\dots,s_m)[X]\), where \(s_1,\dots,s_m\) are ...
openaire +3 more sources