Results 241 to 250 of about 828,807 (306)

On quivers, spectral networks and black holes. [PDF]

Lett Math Phys
Arnaudo P, Grassi A, Hao Q.
europepmc   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

A Bioequivalence Study of Two Formulations of Enzalutamide Soft Capsules in Healthy Chinese Male Subjects. [PDF]

Clin Pharmacol Drug Dev
Wang J, Gu K, Zhang M, Yu M, Zhao P, Yu J, Guo X, Bai Y, Liu J, Wang X, Yang X.   +10 more
europepmc   +1 more source

Lyssavirus Nucleoprotein Induces GPAT4‐Mediated CYB5R1 Depalmitoylation to Suppress Ferroptosis and Promote Viral Replication

Advanced Science, EarlyView.
Lipid metabolism plays a vital role in viral infections. Here, we reveal that the lyssavirus N protein regulates GPAT4 to induce lipid droplet biogenesis, restricting CYB5R1 palmitoylation and reducing ferroptosis susceptibility to ultimately promote viral replication.
Jianqing Zhao, Chuan Liang, Pingping Chen, Meixin Sun, Zhen F. Fu, Ling Zhao, Ming Zhou   +6 more
wiley   +1 more source

Financial Impact of Treatment Choice in Chronic Myeloid Leukemia: A Comparison of Later Generation TKIs versus Imatinib from Patient and Payer Perspectives. [PDF]

Clinicoecon Outcomes Res
Vaughn JE, Zawadzki N, Zhang S, Pinkston P, Wei D, Shafrin J.   +5 more
europepmc   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Generic vs. brand-name pramipexole: effectiveness, safety, and cost comparison in a multicenter retrospective cohort study. [PDF]

Front Aging Neurosci
Wang K, Xing X, Wang Z, Zhang X, Li J, Zhu Y, Guo H, Yu C, Zhang L, Dong X.   +9 more
europepmc   +1 more source

TRPM8 virtual screening: the essential role of target-specific, inactive-enriched machine-learning scoring functions.

Digit Discov
James N, Ballester PJ.
europepmc   +1 more source

Comparative Analysis of <i>SMN2</i> Splicing Activity and Protein Production Following In Vitro Treatment with the Generic Risdiplam Drug Vapromin^® and the Reference Drug Evrysdi^®. [PDF]

Biomedicines
Strizhakova O, Pershin A, Bahareva Y, Kazarov A, Lyagoskin I, Bocharova E, Anisimov R, Gladchenko Y, Kholod N, Kirik I, Gudilina A, Shukurov R, Khamitov R.   +12 more
europepmc   +1 more source