Results 101 to 110 of about 2,442,464 (298)
, 2010 Перед врачом в повседневной практике возникает непростой вопрос выбора препарата для лечения: оригинальный препарат или генерик? Результаты исследования, проведены в лаборатории «ACC GmbH Analytical Concepts» (Германия), свидетельствуют о том, что ...
Гайдукова, С.Н. +1 more
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Does Pharmaceutical Price Regulation Affect the Adoption of Generic Competition? Evidence from the OECD, 1999-2008 [PDF]
Generic competition in the pharmaceutical market is an effective cost-containment mechanism that improves static efficiency and stimulates pharmaceutical innovation. There is no prior study that has empirically analysed the relative delays in adoption of
Nebibe Varol +2 more
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Generic Drug User Fee Act II: The positive features for generic drug industry
, 2017 The US Food and Drug Administration (FDA) and the Generic Drug Industry have completed negotiations for the reauthorization of the Generic Drug User Fee Act (GDUFA II).
Darshit Patel, Jignesh Prajapati
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Advanced Science, EarlyView.Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song +9 more
wiley +1 more source
Effect of Oregon grape root extracts on P-glycoprotein mediated transport in in vitro cell lines
Journal of Pharmacy & Pharmaceutical SciencesPurpose: This study aims to investigate the potential of Oregon grape root extracts to modulate the activity of P-glycoprotein.Methods: We performed 3H-CsA or 3H-digoxin transport experiments in the absence or presence of two sources of Oregon grape root
Ying Fan, Zhu Zhou, Lei Zhang
doaj +1 more source
Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies
Advanced Science, EarlyView.This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan +5 more
wiley +1 more source
Advanced Science, EarlyView.Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
In Vitro Oral Cavity Permeability Assessment to Enable Simulation of Drug Absorption
PharmaceuticsBackground/Objectives: The oral cavity represents a convenient route of administration for drugs that exhibit significant hepatic first-pass extraction. In this study, the mucosal permeation properties of selected active pharmaceutical ingredients (APIs)
Pankaj Dwivedi +7 more
doaj +1 more source
The Distortionary Effects of Government Procurement: Evidence from Medicaid Prescription Drug Purchasing [PDF]
The federal-state Medicaid program insures 43 million people for virtually all of the prescription drugs approved by the FDA. To determine the price that it will pay for a drug treatment, the government uses the average price in the private sector for ...
Mark Duggan, Fiona Scott Morton
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Generic Drug Policies in Latin America
, 2005 The World Health Organization and pharmaceutical experts have recommended that Generic Drug Policies be implemented to improve the availability of affordable medicines. This document reports on the status of
Homedes, Núria +2 more
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