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Model Master File Framework: A Regulatory Path Advancing Modeling and Simulation Applications [PDF]

open access: yesClinical and Translational Science
To advance drug product development, regulatory decision making, and improve patient care, FDA has committed to the quantitative medicine paradigm that involves, among others, quantitative in silico methodologies and tools developed based on nonclinical,
Eleftheria Tsakalozou   +4 more
doaj   +2 more sources

Time series analysis of the new tiering pricing policy for generic medicines in South Korea [PDF]

open access: yesFrontiers in Pharmacology
BackgroundSouth Korea introduced a new tiered pricing policy for generic medicines in July 2020, linking reimbursement to bioequivalence testing and active pharmaceutical ingredient registration requirements.
Chan Mi Park   +2 more
doaj   +2 more sources

Migration to Intermediate XML for Electronic Data (MIXED): Repository of Durable File Format Conversions

open access: yesInternational Journal of Digital Curation, 2011
Data Archiving and Networked Services (DANS), the Dutch scientific data archive for the social sciences and humanities, is engaged in the Migration to Intermediate XML for Electronic Data (MIXED) project to develop open source software that implements ...
René van Horik, Dirk Roorda
doaj   +11 more sources

Distributed Big Data Storage Infrastructure for Biomedical Research Featuring High-Performance and Rich-Features

open access: yesFuture Internet, 2022
The biomedical field entered the era of “big data” years ago, and a lot of software is being developed to tackle the analysis problems brought on by big data. However, very few programs focus on providing a solid foundation for file systems of biomedical
Xingjian Xu, Lijun Sun, Fanjun Meng
doaj   +1 more source

A GENERIC RIGOROUS SENSOR MODEL FOR PHOTOGRAMMETRIC PROCESSING OF PUSHBROOM PLANETARY IMAGES [PDF]

open access: yesThe International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2019
Currently, each planetary exploration mission team always develops its own software modules to support the photogrammetric processing of planetary images, and as a result of that the main drawbacks are lacking software reusability and the high cost of ...
X. Geng, X. Geng, S. Xing, Q. Xu
doaj   +1 more source

Climate data for hygrothermal simulations of Brussels

open access: yesData in Brief, 2022
Moisture is a dominant agent in the degradation of building components. To assess degradation phenomena in building envelopes, hygrothermal simulations are performed.
Isabeau Vandemeulebroucke   +2 more
doaj   +1 more source

A Formal Model of a Virtual Filesystem Switch [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2012
This work presents a formal model that is part of our effort to construct a verified file system for Flash memory. To modularize the verification we factor out generic aspects into a common component that is inspired by the Linux Virtual Filesystem ...
Jörg Pfähler   +4 more
doaj   +1 more source

A Generic Pushbroom Sensor Model for Planetary Photogrammetry

open access: yesEarth and Space Science, 2020
Different imaging instruments are designed in the planetary exploration missions, which require respective photogrammetric software modules to support the geometric processing of planetary remote sensing images.
Xun Geng   +3 more
doaj   +1 more source

Method for Using IMU-Based Experimental Motion Data in BVH Format for Musculoskeletal Simulations via OpenSim

open access: yesSensors, 2023
Biomechanical simulation allows for in silico estimations of biomechanical parameters such as muscle, joint and ligament forces. Experimental kinematic measurements are a prerequisite for musculoskeletal simulations using the inverse kinematics approach.
Iris Wechsler   +9 more
doaj   +1 more source

Machine Learning-based Anomaly Detection of Ganglia Monitoring Data in HEP Data Center [PDF]

open access: yesEPJ Web of Conferences, 2020
This paper introduces a generic and scalable anomaly detection framework. Anomaly detection can improve operation and maintenance efficiency and assure experiments can be carried out effectively.
Chen Juan, Wang Lu, Hu Qingbao
doaj   +1 more source

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