Results 81 to 90 of about 513,714 (276)

Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif   +17 more
wiley   +1 more source

Toxicities of docetaxel: original drug versus generics—a comparative study about 81 cases

open access: yesSpringerPlus, 2016
IntroductionDocetaxel is a chemotherapy drug widely prescribed in oncology that recognizes a variety of manufactured generics whose toxicity is increasingly reported. The aim of this study was to compare the toxicities between the original and a generics
C. Elm'hadi   +7 more
semanticscholar   +1 more source

An example of a non non-archimedean Polish group with ample generics [PDF]

open access: yes, 2015
For an analytic $P$-ideal $I$, $S_I$ is the Polish group of all the permutations of $\mathbb{N}$ whose support is in $I$, with Polish topology given by the corresponding submeasure on $I$.
Maciej Malicki
semanticscholar   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Perceptions of generic medication in the general population, doctors and pharmacists: a systematic review

open access: yesBMJ Open, 2015
Objective To investigate negative perceptions about generic medicines and evaluate the proportions of lay people, doctors and pharmacists who hold these perceptions.Design A systematic review of observational studies.Data sources MEDLINE, EMBASE ...
Andrew Grey   +5 more
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Initiatives to increase the prescribing of low cost generics: the case of Scotland in the international context

open access: yes, 2017
Getting the most out of the pharmaceutical budget is critical across all countries as the financial pressures on healthcare systems intensify. In this paper, we review global practice on encouraging the use of low costs generics versus branded ...
B. Godman   +19 more
semanticscholar   +1 more source

The content and reporting completeness of physical therapist‐led interventions for glenohumeral osteoarthritis: a systematic review

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study synthesised the content and reporting completeness of published physical therapist‐led interventions for glenohumeral osteoarthritis (GHOA). Methods This systematic review undertook electronic database searches in PubMed, EMBASE, Cochrane, CINAHL and PEDro (until June 2025) for any peer‐reviewed articles/studies describing ...
Daha G Muhammad   +5 more
wiley   +1 more source

Potential Clinical and Economic Impact of Switching Branded Medications to Generics

open access: yesAmerican Journal of Therapeutics, 2015
Switching branded to generic medications has become a common cost-containment measure. Although this is an important objective for health care systems worldwide, the impact of this practice on patient outcomes needs to be carefully considered.
R. Straka, D. Keohane, Larry Z. Liu
semanticscholar   +1 more source

Memristive‐Gated RC‐Delay Synaptic Transistors for Time‐Encoded Analog in‐Memory Computing

open access: yesAdvanced Functional Materials, EarlyView.
A Memristive‐Gated Transistor for Time‐Encoded Analog In‐Memory Computing — By exploiting the RC delay of a self‐rectifying interface‐type memristor, nonlinear I–V distortion is structurally bypassed, enabling 3‐bit nonvolatile memory, spike‐timing‐based analog encoding, and hardware‐calibrated reservoir‐computing validation within a unified device ...
Yun‐Seo Shin   +7 more
wiley   +1 more source

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