Results 251 to 260 of about 1,208,813 (315)

Antibiotic resistance gene analyses in microbial communities: challenges and opportunities. [PDF]

Nat Commun
Larsson DGJ, Flach CF, Kristiansson E.
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Bacteriophages as Antibacterial Agents Against Bovine Pathobionts Associated with Foodborne Human Morbidity. [PDF]

Viruses
Garvey M.
europepmc   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

Advanced Science, EarlyView.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang, Zhaxi Zerang, Linjin You, Ziye Liu, Rong Nie, Fuwei Qi, Fenfen Gao, Chengmu Zhao, Wantong Ma, Jinghan He, Xiaoru Wang, Shanquan Wu, Bo Liu, Xinyao Liu, Dongsheng Lei, Dejuan Zhi, Dongsheng Wang   +16 more
wiley   +1 more source

Linking Bacterial r/k Ecological Shifts to Spatiotemporal Nitrogen Removal Dynamics in Recirculating Aquaculture Systems. [PDF]

Microb Ecol
Hu C, Lin M, Hu T, Zeng Y, Zeng R, Wang C.   +5 more
europepmc   +1 more source

Divergent roles of OmpA family proteins in physiology, stress tolerance, and virulence of <i>Elizabethkingia miricola</i>. [PDF]

Virulence
Liu F, He F, Gu Z, Hu R.
europepmc   +1 more source

<i>Bacillus subtilis</i> G01: A Multifunctional Agent with Broad-Spectrum Antimicrobial Activity and Digestive Enzymes for Sustainable Agriculture and Animal Husbandry. [PDF]

J Microbiol Biotechnol
Yan Y, Lin J, Chen D, Pi J, Xu JF, Zhong X, Chen L.   +6 more
europepmc   +1 more source

Downregulation of motility during stress requires stressosome input in <i>Listeria monocytogenes</i> strain EGD-e. [PDF]

Appl Environ Microbiol
Tiensuu T, Guerreiro DN, Ignatov D, Oliveira AH, O'Byrne C, Johansson J.   +5 more
europepmc   +1 more source