Results 111 to 120 of about 548,379 (312)
Kidney & Blood Pressure Research, 2019 Background/Aims: Autosomal dominant polycystic kidney disease (ADPKD) is the most common genetic form of kidney disease. High-throughput microarray analysis has been applied for elucidating key genes and pathways associated with ADPKD.
Dongmei Liu +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
KEGG pathways significantly enriched in genes that are overexpressed in Dominant Red skin samples. [PDF]
, 2015 KEGG pathways significantly enriched in genes that are overexpressed in Dominant Red skin samples.
Leif Andersson (42573) +11 more
core +1 more source
Dominance Modification and Physiological Effects of Genes [PDF]
Proceedings of the National Academy of Sciences, 1945 L C, Dunn, S, Gluecksohn-Schoenheimer
openaire +3 more sources
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Identification and characterization of TNFalpha responsive genes in human breast cancer cells [PDF]
, 2006 One of the hallmarks of cancer is the escape of the transformed cells from apoptosis. Therefore, the identification of survival genes, allowing cancer cells to circumvent programmed cell death, could provide new diagnostic markers as well as targets for ...
Guardiola Serrano, Francisca
core
Relative importance of the epistatic components of genotypic variance in non-inbred populations
Crop Breeding and Applied Biotechnology, 2004 There are theoretical approaches about genic interaction in polygenic systems and methodologies to confirm its occurrence. However, some relevant aspects as the relative importance of the epistatic components of genotypic variance deserve further ...
José Marcelo Soriano Viana
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Plant-Microbe Interactions, 2005 Tomato powdery mildew caused by Oidium neolycopersici has become a globally important disease of tomato (Lycopersicon esculentum). To study the defense responses of tomato triggered by tomato powdery mildew, we first mapped a set of resistance genes to O.
Yuling Bai +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source