Results 171 to 180 of about 25,117 (218)

Dysregulated immunometabolism in gut inflammation. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Zheng M, Tian Q, Shen J, Li S.
europepmc   +1 more source

Unspoken words: decoding the dialog between type 2 innate lymphoid cells and T cells. [PDF]

Front Immunol
Ikra ZJ, Huang Q, Yu H, Belz GT, Jenne CN, Jacquelot N.   +5 more
europepmc   +1 more source

Whipworm infection remodels the gut microbiome ecosystem and compromises intestinal homeostasis in elderly patients revealed by multi-omics analyses. [PDF]

Front Cell Infect Microbiol
Zhang B, Sheng Z, Bu C, Wang L, Lv W, Wang Y, Xu Y, Yan G, Gong M, Liu L, Hu W.   +10 more
europepmc   +1 more source

HpBoRB, a helminth-derived CCP domain protein which binds RELMβ

Shek V, Jamwal A, Smyth DJ, Frangova T, Savage AR, Kelly S, Wright GJ, Toth R, Maizels RM, Higgins MK, Ivens AC, Smits HH, McSorley HJ.   +12 more
europepmc   +1 more source

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Gene manipulation in parasitic helminths

International Journal for Parasitology, 2003
In light of recent growth in available DNA sequence information for a number of parasitic helminths, it is crucial that suitable gene manipulation technologies are developed to facilitate functional genomic studies in these organisms. In this review we discuss recent progress in the development of these technologies in nematode and platyhelminth ...
Jon P, Boyle, Timothy P, Yoshino
openaire   +2 more sources

Helminth genomics: from gene discovery to genome sequencing

Trends in Parasitology, 2002
Abstract A joint meeting of the World Health Organisation-funded Schistosome and Filarial Genome Networks was held at The Institute for Genomic Research (TIGR, Rockville, MD, USA) from 10th to 12th January 2002.
Foster, Jeremy M, Johnston, David A
openaire   +2 more sources

Digital gene expression analysis of gastrointestinal helminth resistance in Scottish blackface lambs

Molecular Ecology, 2011
AbstractDigital gene expression (DGE) analysis offers a route to gene discovery which by‐passes the need to develop bespoke arrays for nonmodel species, and is therefore a potentially valuable tool for molecular ecologists. Scottish blackface sheep, which vary in resistance to the common abomasal parasitic nematode Teladorsagia circumcincta, were ...
J M, Pemberton, D, Beraldi, B H, Craig, J, Hopkins   +3 more
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Tubulin-gene Mutation in Drug Resistance in Helminth Parasite: Docking and Molecular Dynamics Simulation Study

Current Chemical Biology, 2023
Background: Drug resistance is an important phenomenon in helminth parasites. Microtubules are among the key chemotherapeutic targets, mutations of which lead to drug resistance. Objectives: The present study investigated the role of F167Y, E198A, and F200Y mutations in β- tubulin protein and their effect on albendazole binding.
Ananta Swargiary, Harmonjit Boro, Dulur Brahma   +2 more
openaire   +1 more source

Prediction of gene expression and codon usage in human parasitic helminths

Genes & Genomics, 2015
Codon usage bias refers to the differences in the occurrence frequency of synonymous codons. To understand the patterns of codon usage in mitochondrial genes we used bioinformatic approaches to analyze the protein coding sequences of W. bancrofti and S. haematobium as no work was reported earlier.
Gulshana A. Mazumder, Arif Uddin, Supriyo Chakraborty   +2 more
openaire   +1 more source

Proteinases and Associated Genes of Parasitic Helminths

1999
Many parasites have deployed proteinases to accomplish some of the tasks imposed by a parasitic life style, including tissue penetration, digestion of host tissue for nutrition and evasion of host immune responses. Information on proteinases from trematodes, cestodes and nematode parasites is reviewed, concentrating on those worms of major medical and ...
J, Tort, P J, Brindley, D, Knox, K H, Wolfe, J P, Dalton   +4 more
openaire   +2 more sources