Results 201 to 210 of about 23,322 (214)
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Use of chitinase to facilitate detection of protozoan, helminth and single copy genes in squashed whole mosquitoes

Molecular and Biochemical Parasitology, 1989
The application of DNA probes to detect foreign DNA in whole arthropods has been limited by the inability of the probes to distinguish between small quantities of target DNA and the background signal generated by non-specific hybridization of mosquito material.
Betty Kim Lee Sim   +6 more
openaire   +3 more sources

Tubulin-gene Mutation in Drug Resistance in Helminth Parasite: Docking and Molecular Dynamics Simulation Study

Current Chemical Biology, 2023
Background: Drug resistance is an important phenomenon in helminth parasites. Microtubules are among the key chemotherapeutic targets, mutations of which lead to drug resistance. Objectives: The present study investigated the role of F167Y, E198A, and F200Y mutations in β- tubulin protein and their effect on albendazole binding.
Ananta Swargiary   +2 more
openaire   +1 more source

Development of primers for the mitochondrial cytochrome c oxidase I gene in digenetic trematodes (Platyhelminthes) illustrates the challenge of barcoding parasitic helminths

Molecular Ecology Resources, 2009
AbstractThe phylum Platyhelminthes is a diverse group of flatworms that includes parasites with serious impacts on human health, animal husbandry, aquaculture and wildlife management. Here we present degenerate primers for the barcode region of the mitochondrial cytochrome c oxidase I (COI) gene in flatworms.
Anna Moszczynska   +4 more
openaire   +2 more sources

Multiple Lineages of the Mitochondrial Gene NADH Dehydrogenase Subunit 1 (ND1) in Parasitic Helminths: Implications for Molecular Evolutionary Studies of Facultatively Anaerobic Eukaryotes

Journal of Molecular Evolution, 2000
The task of using partial ND1 sequences to infer a phylogeny for species of the genus Paragonimus (Trematoda: Digenea) was complicated by the discovery of at least two ND1 lineages within individual worms. The divergence of the ND1 lineages is shown by phylogenetic analysis not only to predate the divergence of the three Paragonimus species or species ...
Van Herwerden, Lynne   +2 more
openaire   +4 more sources

Temporal Changes in MRI Activity, Inflammation, Immunomodulation, and Gene Expression in Relapsing-Remitting Multiple Sclerosis Subjects Treated with Helminth Probiotic Trichuris Suis (S30.004)

Neurology, 2012
Objective: To define critical points at which immunological markers and gene expression patterns correlate with changes in brain MRI activity during treatment with Trichuris suis ova (TSO) in the HINT clinical trial for relapsing-remitting multiple sclerosis (RRMS).
Christina Kendziorski   +8 more
openaire   +2 more sources

Workshop 1M: Helminth antigens and genes

International Journal for Parasitology, 1987
M.J. Howell, R.M.E. Parkhouse
openaire   +2 more sources

The helminth Schistosoma mansoni expresses a peptide similar to human beta-endorphin and possesses a proopiomelanocortin-related gene.

The New biologist, 1991
Opioid peptides, a group of transmitter substances with a high degree of phylogenic conservation, have many different functions, including a role in modulation of cells of the immune system. We have postulated the existence of such peptides in the parasite Schistosoma mansoni in view of their possible role in host-parasite interactions.
O, Duvaux-Miret   +5 more
openaire   +1 more source

Parasitic helminths: genes, membranes and antigens II

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1991
openaire   +2 more sources

The assessment of single nucleotide polymorphisms in the ß-tubulin genes in human soil-transmitted helminths exposed to different pressure with benzimidazole drugs

AbstractBackgroundWe aimed to gain insights into the role of known single nucleotide polymorphisms (SNPs) in codons 167, 198 and 200 of the ß-tubulin gene as markers for possible benzimidazole resistance in human soil-transmitted helminths (STHs;Ascaris lumbricoides, Trichuris trichiura,Necator americanusandAncylostsoma duodenale).MethodsFirstly, we ...
Bruno Levecke   +15 more
openaire   +1 more source

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