Results 81 to 90 of about 24,986 (221)

Genotypic profile of benzimidazole resistance associated with SNP F167Y in the beta-tubulin gene of Necator americanus helminths obtained from Brazilian populations

Infection, Genetics and Evolution, 2020
Necator americanus is a worm that parasites the small intestine of humans and is highly prevalent in regions with poor sanitary conditions. The main strategy to control this helminth is by mass benzimidazole administration, however, periodic use of these drugs can select strains of parasites resistant to treatment. Single nucleotide polymorphisms (SNPs)
Luis Fernando Viana Furtado, Talita Rodrigues dos Santos, Valéria Nayara Gomes Mendes de Oliveira, Élida Mara Leite Rabelo   +3 more
openaire   +2 more sources

Emerging mechanisms of ILC2‐neuronal crosstalk across the body

Immunology &Cell Biology, EarlyView.
Emerging roles of ILC2 in neuronal crosstalk across organs. In a series of studies published in 2025, ILC2 were shown to regulate nervous system function across a range of organs across the body. Within the intestinal tract, ILC2‐derived cytokines acted on enteric neurons to orchestrate immunity to helminths (Wang et al).
David A Posner, Matthew R Hepworth
wiley   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Low-dose intestinal Trichuris muris infection alters the lung immune microenvironment and can suppress allergic airway inflammation [PDF]

, 2016
Immunological cross talk between mucosal tissues such as the intestine and the lung is poorly defined during homeostasis and disease. Here, we show that a low-dose infection with the intestinally restricted helminth parasite Trichuris muris results in ...
Antignano, Frann, Burrows, Kyle, Chenery, Alistair L., Perona-Wright, Georgia, Scheer, Sebastian, Zaph, Colby   +5 more
core   +7 more sources

Therapeutic helminth infection of macaques with idiopathic chronic diarrhea alters the inflammatory signature and mucosal microbiota of the colon.

PLoS Pathogens, 2012
Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompanied ...
Mara Jana Broadhurst, Amir Ardeshir, Bittoo Kanwar, Julie Mirpuri, Uma Mahesh Gundra, Jacqueline M Leung, Kirsten E Wiens, Ivan Vujkovic-Cvijin, Charlie C Kim, Felix Yarovinsky, Nicholas W Lerche, Joseph M McCune, P'ng Loke   +12 more
doaj   +1 more source

Th2-dependent STAT6-regulated genes in intestinal epithelial cells mediate larval trapping during secondary Heligmosomoides polygyrus bakeri infection.

PLoS Pathogens, 2023
Gastrointestinal helminths are a major health threat worldwide. Alternatively activated macrophages (AAMs) have been shown to contribute to host protection during secondary helminth infections. AAMs express effector molecules that depend on activation of
Stefanie Westermann, Christoph Schubart, Axel Dietschmann, Kirstin Castiglione, Daniel Radtke, David Voehringer   +5 more
doaj   +1 more source

Novel expression of Haemonchus contortus vaccine candidate aminopeptidase H11 using the free-living nematode Caenorhabditis elegans [PDF]

, 2013
With the problem of parasitic nematode drug resistance increasing, vaccine development offers an alternative sustainable control approach. For some parasitic nematodes, native extracts enriched for specific proteins are highly protective.
Antonopoulos, A., Britton, C., Dell, A., Dicker, A.J., Haslam, S.M., Johnston, S.L., Knox, D.P., Mcneilly, T.N., Roberts, B.   +8 more
core   +3 more sources

Pejerrey (Odontesthes bonariensis) Under Siege: Main Infectious Diseases and Their Role in Aquaculture and Wild Populations Amidst Environmental Change

Journal of Fish Diseases, Volume 48, Issue 4, April 2025.
ABSTRACT The pejerrey (Odontesthes bonariensis) is a key species for recreational and commercial fisheries in Argentina and holds significant aquaculture potential. It has been introduced to various countries worldwide, including Japan, where intensive aquaculture has developed.
Aarón Torres‐Martínez, Miguel Mancini, Fabian Grosman, Gustavo Manuel Somoza, Carlos Augusto Strüssmann   +4 more
wiley   +1 more source

Immune endotypes in tuberculosis: Keys to decoding disease complexity

Journal of Internal Medicine, EarlyView.
Abstract Tuberculosis (TB) remains a major global health challenge, with multi‐drug antibiotic regimens as the current standard of care. While effective at killing Mycobacterium tuberculosis, these treatments do not resolve persistent inflammation, prevent lung damage, or reverse immune dysregulation that contribute to poor outcomes and disease ...
Shamila D. Alipoor, Julia Guthrie, Lina Davies Forsman, Andrew R. Di Nardo, Susanna Brighenti   +4 more
wiley   +1 more source

Anisakis pegreffii impacts differentiation and function of human dendritic cells [PDF]

, 2018
Human dendritic cells (DCs) show remarkably phenotypic changes when matured in presence of helminth-derived products. These modifications frequently elicited a polarization towards Th2 cells and regulatory T cells thus contributing to immunological ...
Allen, Alonso-Gómez, Annunziato, Aranzamendi, Babal, Baeza, Battisti, Becher, Blanco, Coakley, Cortés, Cvetkovic, D'Amelio, Das Mohapatra, Daschner, Dowling, Entwistle, Gerbe, Giri, Gruden-Movsesijan, Hall, Hartmann, Hiemstra, Iborra, Ivanova, Johnson, Klaver, Kotsias, Kuijk, Lian, Lim, Mattiucci, Mattiucci, Mattiucci, Mattiucci, Mattiucci, Mattiucci, Mattiucci, Mattiucci, Messina, Mladineo, Morris, Motran, Nakahara, Nieuwenhuizen, Pulendran, Rescigno, Rodríguez, Rughetti, Silva, Swofford, Terrazas, Ueno, Umehara, Witkowska, Zizzari   +55 more
core   +1 more source