Results 131 to 140 of about 9,871,845 (257)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

The epigenetic landscape of plant defense: Unlocking nature's toolkit for new plant protection

New Plant Protection, EarlyView.
This review examines how epigenetic mechanisms regulate plant immune gene activation, repression, and priming, then links these natural regulatory layers to emerging epigenetic editing, discussing their potential for precise, heritable crop protection and the challenges.
Xuexia Liu, Zhenhui Zhong
wiley   +1 more source

Impact of plant breeding on the responsiveness of maize and wheat varieties to an arbuscular mycorrhizal fungal symbiont

PLANTS, PEOPLE, PLANET, EarlyView.
Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog, Marco Malinowski, Dylan Baumann, Raphaël Boussageon, Stefanie Lutz, Marcel G. A. van der Heijden   +5 more
wiley   +1 more source

Mating-Type Switching and Recombination Associated with Mating-Type Loci in Model and Pathogenic Yeasts

, 2013
In S. cerevisiae, mating-type switching is triggered by a DSB generated at the MAT locus by the HO endonuclease, and a gene conversion event occurs between MAT and a silent cassette, usually the one which encodes the opposite mating type.
Joseph Heitman (22335), Yen-Ping Hsueh (152822), Alexander Idnurm (58590)   +2 more
core   +1 more source

Plant species are more important to bacterial community composition than seeding ratio in a pea‐canola intercropping system

PLANTS, PEOPLE, PLANET, EarlyView.
Demand for agricultural land has increased due to rising demand for food, potentially leading to expansion into previously untouched habitats, which threatens refugia of native plants. We aimed to provide insight into how variation in seeding ratio may impact soil bacterial communities in a pea‐canola intercropping system, potentially altering crop ...
Janice M. Parks, Braeden J. Stiffler, Maren L. Friesen   +2 more
wiley   +1 more source

Multiple barriers maintain species boundaries in sympatric brood‐site deceptive Gastrodia orchids

PLANTS, PEOPLE, PLANET, EarlyView.
Gastrodia orchids are inconspicuous forest plants that lack chlorophyll and obtain carbon from fungi. Their dull‐colored, ground‐level flowers are often hidden among leaf litter, yet they rely on small flies for pollination. We show that two co‐occurring Gastrodia species remain distinct even though they share similar pollinators.
Kenji Suetsugu, Akihiro Nishimura, Shun K. Hirota, Masahito T. Kimura   +3 more
wiley   +1 more source

Arbuscular mycorrhizal fungi enhance plant performance in trace element‐contaminated soils with element‐specific accumulation patterns

PLANTS, PEOPLE, PLANET, EarlyView.
Soil contamination by toxic trace elements is a growing global challenge that threatens food safety, agricultural productivity, and ecosystem health. We combined results from many experiments worldwide to assess whether beneficial soil fungi can help plants cope with contaminated soils.
Zahraddeen Kabir Sani, Jean Legeay, Mohamed Hijri   +2 more
wiley   +1 more source

An extinction‐emergency metacollection: Maximising future recovery options for Rhodomyrtus psidioides (Myrtaceae), threatened by Myrtle Rust

PLANTS, PEOPLE, PLANET, EarlyView.
A challenge for wild plant conservation is the rising incidence of plant pathogens that are difficult to interdict, contain and manage. Invasive, fast‐moving, broad‐spectrum pathogens impose societal costs through losses of intrinsically valuable wild biodiversity, ecosystem function, current and potential genetic and biological assets, culturally ...
Robert O. Makinson, Veronica Viler, Amelia J. Martyn Yenson, Craig Stehn, Fiona R. Giblin, Catherine A. Offord, Philippa Walsh, Chantelle A. T. Doyle   +7 more
wiley   +1 more source

A putative nursery pollination mutualism between Japanese Chrysosplenium plants and Nipponorhynchus sawflies

PLANTS, PEOPLE, PLANET, EarlyView.
Understanding ecological interactions is increasingly important for biodiversity conservation. This study reveals a unique nursery pollination mutualism between Japanese endemic plants and sawflies. These partners exhibit tightly synchronized life cycles in riparian forests, making them sensitive to environmental changes.
Marika Yamaguchi, Hideo Takahashi, Namiki Kikuchi, Takahiro Yoshida, Noriaki Murakami, Yudai Okuyama   +5 more
wiley   +1 more source