Results 201 to 210 of about 9,871,845 (257)

Identification of a master regulator Msd1 that governs meiotic entry in a global basidiomycete pathogen. [PDF]

Proc Natl Acad Sci U S A
Zheng F, Cao Y, Chen H, Yan L, Lv F, Huang Y, Chen M, Su L, Liu Z, Huang Y, Pham T, Xu X, Lin X.   +12 more
europepmc   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source

Natural product‐derived TRPM7 channel inhibitors in neurological injury: Mechanisms, pharmacological potential and translational challenges

British Journal of Pharmacology, EarlyView.
Disruption of intracellular ionic homeostasis is a convergent pathological feature across diverse neurological injuries and disorders, including ischaemic and haemorrhagic stroke, hypoxic–ischaemic brain injury, traumatic brain injury, epilepsy and brain tumour.
Xinyang Zhang, Hio Lam Ho, F. David Horgen, Andrea Fleig, Zhong‐Ping Feng, Hong‐Shuo Sun   +5 more
wiley   +1 more source

Molecular analysis of fungal mating type genes

, 2016
openaire   +1 more source

Mutations in the SdhB and SdhD Genes Confer Resistance to Succinate Dehydrogenase Inhibitor Fungicides in Australian Populations of Leptosphaeria maculans. [PDF]

Mol Plant Pathol
Tsao KH, Idnurm A, Van de Wouw AP, McCallum AJ.   +3 more
europepmc   +1 more source

Advances in Spatial Heterogeneity and Cellular Localization Specificity of Intratumoral Bacteria

Cancer Science, EarlyView.
Spatial localization of intratumoral bacteria governs their functional roles in tumor progression, metastasis, and treatment responses, with guiding significance for clinical management, as reviewed across three spatial paradigms. ABSTRACT Bacteria in tumors are increasingly recognized to be a part of the tumor microenvironment and their biological ...
Minlan Ren, Jing Jia, Tingting Li, Yiwei Li, Nanxiang Shen, Yun Shi, Zhe Wang, Hao Fan, Guangli Sun, Guanying Xiong, Gang Li, Rui Peng   +11 more
wiley   +1 more source

Temperature during conidiophore development primes <i>Aspergillus fumigatus</i> spore transcriptome for asexual or sexual reproduction. [PDF]

mBio
Stanislaw JM, Momany M.
europepmc   +1 more source

Larval character evolution in Holometabola (Insecta)

Cladistics, EarlyView.
Abstract Larvae, a novel type of immature stage, are a crucial innovation of the Holometabola. Larval features therefore provide key evidence for reconstructing evolutionary transformations in this megadiverse group. Here we present the first formal reconstruction of larval character evolution, using maximum parsimony and Bayesian ancestral‐state ...
Rolf Georg Beutel, Jakub Goczał, Di Li
wiley   +1 more source

Population genomics of the Japanese oak wilt pathogen reveals genetic structure mirroring its beetle vector and informs biosecurity risk assessment. [PDF]

BMC Genomics
Dobbs JT, Koch-Bach R, Stone C, Crouch JA.   +3 more
europepmc   +1 more source

The commercial trade in exotic pets has had little impact on wild populations of reptiles and amphibians

Conservation Biology, EarlyView.
Abstract The commercial trade in exotic pets has raised concerns about population‐level impacts from collection in the wild; however, proponents of the trade claim that such concerns are unfounded. To resolve this debate, more information is needed on the volume of the pet trade, the species involved, their conservation status in the wild, and the ...
Richard Shine, Melanie J. Elphick, Mark O'Shea, Nicholas P. Vine   +3 more
wiley   +1 more source