Results 191 to 200 of about 759,014 (317)

The Transcriptional Regulator TRG1 Plays a Role in Regulating Peptaibol Biosynthesis in <i>Trichoderma longibrachiatum</i>. [PDF]

J Microbiol Biotechnol
Hu W, Ren A, Guan M, Wang X, Li M, Zhang X, Zhao P.   +6 more
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Analysis of Putative CzcR Targets Under Zinc Sufficiency and Zinc Excess Conditions in <i>Pseudomonas aeruginosa</i> Using ChIP-Seq. [PDF]

Microorganisms
Mauffrey F, Ducret V, Milho CG, Perron K.   +3 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

A novel GntR-ABC efflux system mediates oxidative stress response, drug resistance, motility and virulence in <i>Acinetobacter baumannii</i> ATCC 17978. [PDF]

Front Microbiol
Corral J, Pérez-Varela M, Sánchez-Osuna M, Gaona M, Campoy S, Barbé J, Aranda J.   +6 more
europepmc   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Effect of Small Nucleolar RNA H/ACA Box 64 (SNORA64) on Apoptosis Regulator Genes in Pancreatic Cancer in Vitro. [PDF]

F1000Res
Alfardan R.
europepmc   +1 more source

Genes and gene regulation

The Journal of Physical Fitness and Sports Medicine, 2018
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cells. [PDF]

Inflamm Res
Yoon HS, Ma S, Kanke M, Wu WJ, Hoang U, Tan JA, Wilks A, Patel P, Chandra S, Luo X, Lu D, Martin S, Wilson M, Van Lookeren Campagne M, Li CM, Kao CY.   +15 more
europepmc   +1 more source