Results 121 to 130 of about 69,784 (168)

Identifying expression and DNA methylation biomarkers for lung adenocarcinoma risk in East Asia. [PDF]

J Natl Cancer Inst
Chen TY, Chien LH, Jiang SS, Choi J, Hung HH, Hsiao CF, Shi J, Blechter B, Breeze CE, Chang GC, Chen KY, Tsai YH, Su WC, Huang MS, Chen YM, Wen YF, Chen CY, Wang CL, Tsai FY, Chen HL, Hsieh WS, Lin HC, Wang LH, Chen CJ, Yang PC, Chen CY, Rothman N, Chanock SJ, Lan Q, Chang IS, Hsiung CA.   +30 more
europepmc   +1 more source

Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs, Eslam A. Elghonaimy, Praveen Ramakrishnan Geethakumari, Kiran A. Kumar, Joseph F. Merola, Heather W. Goff, Todd A. Aguilera   +6 more
wiley   +1 more source

Vasculitic fasciitis characterizes a distinct subset of vasculitic myopathy with interferon-gamma signature. [PDF]

Acta Neuropathol
Ruffer N, Pinal-Fernandez I, Preusse C, Mammen AL, Holzer MT, Kleefeld F, Goebel HH, Casal-Dominguez M, Pak K, Kötter I, Siefert J, Furth C, Feldhaus F, Görl N, Fieber F, Alten R, Huber TB, Casteleyn V, Roos A, Krusche M, Schneider U, Milisenda JC, Stenzel W.   +22 more
europepmc   +1 more source

High‐throughput multispecies quantitative polymerase chain reaction assays to study the effects of acute thermal stress in three species of Acipenser sturgeon

Journal of Fish Biology, EarlyView.
Abstract Fishes experience thermal stress in their natural environment that can be caused by natural or anthropogenic factors and can directly affect their physiology. In this study, we developed a multispecies OpenArray™ qPCR (quantitative polymerase chain reaction) ‘chip’ to measure the effects of acute thermal stress on the mRNA response of ...
Hossein Haghighi, Kyle Madden, William S. Bugg, Faith M. Penny, Scott A. Pavey, Nicholas J. Bernier, Kenneth M. Jeffries   +6 more
wiley   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Angiogenesis-facilitating and inflammation-modulating SIS-based patches coupled with functional peptides for abdominal wall repair. [PDF]

Mater Today Bio
Zou Z, Liu Y, Zhang X, Cao J, Wei P, Huang Y, Jing W, Zhao B, Wang M.   +8 more
europepmc   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte, Jørgen Slots, Henrik Dommisch   +2 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Transcriptomic analysis reveals that BVDV alters immune and metabolic responses to <i>Brucella abortus</i> A19 in RAW264.7 macrophages. [PDF]

Front Vet Sci
Chai Y, Zhang Y, Zhang J, Song S, Fu W, Zhou X, Zhang Y, Lv T, Chen P, Zhang J, Zhang H, Guo J, Wang Z.   +12 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source