Biomarkers Correlating With the Development of Oral Squamous Cell Carcinoma From Leukoplakia
ABSTRACT Background We assessed protein biomarkers expressed in oral leukoplakia (OL) that are associated with the risk of transformation into oral squamous cell carcinoma (OSCC). Methods Tissue sections of OL transforming into OSCC (leuko‐ca), the corresponding OSCC and OL that did not progress to OSCC (leuko‐nonca) were analyzed with global relative ...
Daniel Giglio +8 more
wiley +1 more source
Assessing the Evolutionary Potential of Endangered Populations Using Genomic Analyses of Selection in Ecologically Important Gene Regions. [PDF]
Bolton PE, Schield DR, Kaur D, Gibbs HL.
europepmc +1 more source
Abstract Orthotopic allograft transplantation (OAT) is a significant approach to addressing organ failure. However, persistent immune responses to the allograft affect chronic rejection, which induces OAT vasculopathy (OATV) and organ failure. Porphyromonas gingivalis can infiltrate remote organs via the bloodstream, thereby intensifying the severity ...
Chien‐Sung Tsai +7 more
wiley +1 more source
Crosstalk mediators implicated in the Stevens-Johnson Syndrome through gene regulatory network analysis. [PDF]
Watanabe M +7 more
europepmc +1 more source
Plant‐Based Production of Human Major Histocompatibility Complex Class II Molecules
ABSTRACT Major histocompatibility complex class II (MHC II) protein triggers adaptive immune responses by presenting antigens on antigen‐presenting cells (APCs) to be recognised by CD4+ T cells. Recombinant MHC II proteins are effective for the analysis of peptide‐binding interaction, detection of antigen‐specific T‐cells and clinical testing for donor‐
Abdelaziz Ramadan +8 more
wiley +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon +6 more
wiley +1 more source
<i>Lactiplantibacillus plantarum</i> LPPerfectus001 Alleviating Irritable Bowel Syndrome in Mice by Modulating Gut Microbiota and NF-κB Signaling Pathway. [PDF]
Wang Y +7 more
europepmc +1 more source
Engineered surface strategies to manage dental implant‐related infections
Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source
Understanding exosomes in facial esthetics and skin aging
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron +3 more
wiley +1 more source
A Combined Transcriptomics and Proteomics Approach to Identify Immune Signatures in ANCA-Associated Glomerulonephritis. [PDF]
Stojkic I +15 more
europepmc +1 more source

