Results 61 to 70 of about 7,597,050 (334)

T-Gene: improved target gene prediction [PDF]

open access: yesBioinformatics, 2019
Abstract Motivation Identifying the genes regulated by a given transcription factor (TF) (its ‘target genes’) is a key step in developing a comprehensive understanding of gene regulation. Previously, we developed a method (CisMapper) for predicting the target genes of a TF based solely on the ...
Timothy O’Connor   +3 more
openaire   +4 more sources

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu   +20 more
wiley   +1 more source

Reporte de caso: exclusión de paternidad

open access: yesIatreia, 2010
Actualmente las pruebas de paternidad son realizadas empleando marcadores microsatélites tipo STR´s con el objetivo de establecer probabilidades de exclusión del 99.99% de acuerdo a la Ley 721 de2001 ó excluir a un presunto padre de la paternidad; por ...
William Usaquen   +8 more
doaj  

Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters

open access: yeseLife, 2019
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ...
Nikolai Petkau   +4 more
doaj   +1 more source

Protected subspace Ramsey spectroscopy

open access: yes, 2014
We study a modified Ramsey spectroscopy technique employing slowly decaying states for quantum metrology applications using dense ensembles. While closely positioned atoms exhibit superradiant collective decay and dipole-dipole induced frequency shifts ...
Genes, Claudiu   +3 more
core   +1 more source

On the origins of Mendelian disease genes in man: the impact of gene duplication [PDF]

open access: yes, 2011
Over 3,000 human diseases are known to be linked to heritable genetic variation, mapping to over 1,700 unique genes. Dating of the evolutionary age of these disease-associated genes has suggested that they have a tendency to be ancient, specifically ...
Dickerson, Jonathan E.   +1 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

A Clinical Evaluation of Cardiovascular Emergencies: A Comparison of Responses from ChatGPT, Emergency Physicians, and Cardiologists

open access: yesDiagnostics
Background: Artificial intelligence (AI) tools, like ChatGPT, are gaining attention for their potential in supporting clinical decisions. This study evaluates the performance of ChatGPT-4o in acute cardiological cases compared to cardiologists and ...
Muhammet Geneş, Bülent Deveci
doaj   +1 more source

Atom-mirror cooling and entanglement using cavity Electromagnetically Induced Transparency

open access: yes, 2011
We investigate a hybrid optomechanical system comprised of a mechanical oscillator and an atomic 3-level ensemble within an optical cavity. We show that a suitably tailored cavity field response via Electromagnetically Induced Transparency (EIT) in the ...
Aurélien Dantan   +5 more
core   +1 more source

MHC-linked and un-linked class I genes in the wallaby [PDF]

open access: yes, 2009
Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Beck, S.   +8 more
core   +4 more sources

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