Results 61 to 70 of about 4,146,284 (322)

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, EarlyView.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Reconstrução do sulco interglúteo: relato de caso Intergluteal sulcus reconstruction: case report

open access: yesRevista Brasileira de Cirurgia Plástica, 2011
INTRODUÇÃO: O conceito de beleza feminina tem mudado ao longo dos anos, porém a forma e a projeção das nádegas permanecem como símbolos de máxima feminilidade.
Genes Lopes de Almeida Junior
doaj   +1 more source

Developmental disruption and restoration of brain synaptome architecture in the murine Pax6 neurodevelopmental disease model

open access: yesNature Communications, 2022
Brain-wide mapping of synapse molecular composition in Pax6 mutant mice shows remodelling and restoration of synaptome architecture during development, a possible means of conferring resilience to genetic disorders.
Laura Tomas-Roca   +7 more
doaj   +1 more source

Gene–Gene and Gene–Environment Interactions in Apolipoprotein L1 Gene-Associated Nephropathy [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
Molecular genetics have revolutionized the understanding of susceptibility to the broad spectrum of kidney diseases with light microscopic appearance of FSGS, particularly in populations with recent African ancestry. These disorders include idiopathic FSGS, HIV-associated nephropathy, severe lupus nephritis, sickle cell nephropathy, and the primary ...
Barry I. Freedman, Karl Skorecki
openaire   +3 more sources

Structural and mechanistic basis for the regulation of the chloroplast signal recognition particle by (p)ppGpp

open access: yesFEBS Letters, EarlyView.
LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra   +7 more
wiley   +1 more source

From gene trees to species trees II: Species tree inference in the deep coalescence model [PDF]

open access: yesarXiv, 2010
When gene copies are sampled from various species, the resulting gene tree might disagree with the containing species tree. The primary causes of gene tree and species tree discord include lineage sorting, horizontal gene transfer, and gene duplication and loss.
arxiv  

A comparison of methods for multiple degree of freedom testing in repeated measures RNA-sequencing experiments

open access: yesBMC Medical Research Methodology, 2022
Background As the cost of RNA-sequencing decreases, complex study designs, including paired, longitudinal, and other correlated designs, become increasingly feasible.
Elizabeth A. Wynn   +3 more
doaj   +1 more source

Gene-Gene Cooperativity in Small Networks [PDF]

open access: yesBiophysical Journal, 2009
22 pages, 10 ...
Aleksandra M. Walczak, Peter G. Wolynes
openaire   +4 more sources

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Integration of Differential Gene-combination Search and Gene Set Enrichment Analysis: A General Approach [PDF]

open access: yesarXiv, 2011
Gene Set Enrichment Analysis (GSEA) and its variations aim to discover collections of genes that show moderate but coordinated differences in expression. However, such techniques may be ineffective if many individual genes in a phenotype-related gene set have weak discriminative power.
arxiv  

Home - About - Disclaimer - Privacy