Results 61 to 70 of about 4,979,257 (318)

A Clinical Evaluation of Cardiovascular Emergencies: A Comparison of Responses from ChatGPT, Emergency Physicians, and Cardiologists

open access: yesDiagnostics
Background: Artificial intelligence (AI) tools, like ChatGPT, are gaining attention for their potential in supporting clinical decisions. This study evaluates the performance of ChatGPT-4o in acute cardiological cases compared to cardiologists and ...
Muhammet Geneş, Bülent Deveci
doaj   +1 more source

In vivo and in situ measurements of the digestive characteristics of sainfoin in comparison with lucerne fed to sheep as fresh forages at two growth stages and as hay

open access: yesAnimal, 2008
In vivo and in situ digestive characteristics of sainfoin (Onobrychis viciifolia L., a tannin-rich forage) and lucerne (Medicago sativa L., a tannin-free forage) were compared to evaluate the effects of condensed tannins (CT) and growth stage (vegetative
J Aufrère, M. Dudilieu, C. Poncet
doaj   +1 more source

MHC-linked and un-linked class I genes in the wallaby [PDF]

open access: yes, 2009
Background: MHC class I antigens are encoded by a rapidly evolving gene family comprising classical and non-classical genes that are found in all vertebrates and involved in diverse immune functions.
Wong, Emily S. W.   +39 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Loss of Calretinin in L5a impairs the formation of the barrel cortex leading to abnormal whisker-mediated behaviors

open access: yesMolecular Brain, 2021
The rodent whisker-barrel cortex system has been established as an ideal model for studying sensory information integration. The barrel cortex consists of barrel and septa columns that receive information input from the lemniscal and paralemniscal ...
Mingzhao Su   +6 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Association between smartphone screen time and exaggerated blood pressure response during treadmill exercise testing: a cross-sectional study

open access: yesBlood Pressure
Objective This study aimed to investigate the relationship between exaggerated hypertensive response to exercise (EHRE), mobile phone screen time and daily physical activity levels, with a focus on potential lifestyle-related factors that contribute to ...
Muhammet Geneş, Cem Barçin
doaj   +1 more source

Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters

open access: yeseLife, 2019
Many physiological processes exhibit circadian rhythms driven by cellular clocks composed of interlinked activating and repressing elements. To investigate temporal regulation in this molecular oscillator, we combined mouse genetic approaches and ...
Nikolai Petkau   +4 more
doaj   +1 more source

Gene-Gene Cooperativity in Small Networks [PDF]

open access: yesBiophysical Journal, 2009
22 pages, 10 ...
Walczak, Aleksandra M.   +1 more
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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