Results 231 to 240 of about 47,618 (305)

Tissue‐level heterogeneity in FECD: Descemet's membrane phenotypes and association with TCF4 CTG18.1 expansion†

The Journal of Pathology, EarlyView.
Abstract Late‐onset Fuchs endothelial corneal dystrophy (FECD) is commonly framed as a corneal endothelial disease characterised by guttae accumulation and progressive thickening of Descemet's membrane (DM). However, clinical forms and evolutionary profiles vary widely.
Sayo Maeno, Yoshinori Oie, Chifune Kai, Kohji Nishida   +3 more
wiley   +1 more source

Structural and phylogenetic analyses of umbravirus and umbra-like virus genomes suggest evolution of capsid-like proteins from 30K movement proteins. [PDF]

J Virol
Simon AE, Needham JM, Mikkelsen A, Atallah O.   +3 more
europepmc   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source

Spaceflight alters molecular networks linked to diverse human diseases in a single cellular model. [PDF]

Sci Adv
Al-Ahmadi W, Barnawi R, Hitti EG, Khabar KSA.   +3 more
europepmc   +1 more source

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

PROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong, Yuming Shi, Aleksandra Kozlova, Renata Moravcova, Jason C. Rogalski, Aidan Jamieson, Lance Lansing, Kyung‐Mee Moon, Xiaojing Yuan, Amanda S. Gregoris, Heather Higo, Julia Common, Ida M. Conflitti, Mateus Pepinelli, Lan Tran, Morgan Cunningham, Hosna Jabbari, Syed Abbas Bukhari, Sarah K. French, Rodrigo Ortega Polo, Shelley E. Hoover, Stephen F. Pernal, Pierre Giovenazzo, M. Marta Guarna, Amro Zayed, Leonard J. Foster   +25 more
wiley   +1 more source

Elucidating Alterations in Viral and Human Gene Expression Due to Human Papillomavirus Integration by Using Multimodal RNA Sequencing. [PDF]

Viruses
Tamai K, Kinjo S, Taguchi A, Nagasaka K, Yoshimoto D, Duong AQ, Yamamoto Y, Iuchi H, Mori M, Sone K, Hamada M, Kawana K, Ikeo K, Hirota Y, Osuga Y.   +14 more
europepmc   +1 more source

Lack of Cerebrospinal Fluid α‐Synuclein Seeding in VPS35 D620N‐ and LRRK2 Y1699C‐Linked Parkinson's Disease

Movement Disorders, EarlyView.
Letizia Santinelli, Neringa Pratuseviciute, Lara M. Lange, Teresa Kleinz, Norbert Brüggemann, Linn Streubel‐Gallasch, Meret Möller, Alexander Zimprich, Christof Brücke, Jean‐Marc Good, Norman Griebner, Shalini Padmanabhan, Philip Seibler, Peter Bauer, Wim Vandenberghe, Esther Sammler, Cornelis Blauwendraat, Christine Klein, Max Borsche   +18 more
wiley   +1 more source

Repositories of biocultural diversity: Toward best practices for empowering ethnobotany in digital herbaria

PLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement As herbaria digitize millions of plant specimens, ethnobotanical information associated with them is becoming increasingly accessible. These biocultural data include plant uses, names, and/or management practices of Indigenous Peoples and Local Communities (IPLCs).
Robbie Hart, Viviane Fonseca‐Kruel, Eduardo Dalcin, Estevão da Silva Luís Alexandre, Matthew Pace, Michaela Schmull, Leonardo Beltran‐Rodríguez, Miguel Murguía‐Romero, Diana G. Flores‐Camargo, Cristina Mapes‐Sánchez, Mark Nesbitt, Carolina Romero, Andrew Townesmith, Jan Salick, Alex McAlvay, Kenneth R. Otero‐Walker, Michael J. Balick, Jacob Golan, Bruce Hoffman, Kelsey Leonard, Giulia Mattalia, Guillaume Odonne, Aurora Prehn, Ina Vandebroek   +23 more
wiley   +1 more source

DKC1: a robust prognostic factor and potential therapeutic target in multiple myeloma. [PDF]

J Transl Med
Sun C, Cheng L, Li A, Han Y, Wang Y, Xiao J, Guo Y, Zhang W, Sun L, Xu D, Kong D, Jiang Y, Zheng C.   +12 more
europepmc   +1 more source