Results 111 to 120 of about 329,703 (248)

Coexisting Calcific Aortic Stenosis and Transthyretin Cardiac Amyloidosis: Real‐World Evaluation of Clinical Characteristics and Outcomes

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The coexistence of transthyretin cardiac amyloidosis (ATTR‐CA) and aortic stenosis (AS) is increasingly recognized, but the clinical consequences are unclear.
Ahmad Masri, Yong Chen, A. Carmine Colavecchia, Darrin Benjumea, Aaron Crowley, Priti Jhingran, Matthew Kent, Jenifer Wogen, Cindi Pankratova, Jose Maria Jimenez Alvir, Rahul Bhambri   +10 more
doaj   +1 more source

Localizing value of ecstatic phenomenon in epilepsy surgery: A systematic review

Epileptic Disorders, EarlyView.
Abstract Objective A systematic review was conducted to synthesize current anatomo‐clinical correlations of ecstatic symptoms in focal epilepsy, aiming to provide evidence‐based guidance for interpreting this ictal semiology during presurgical evaluation.
Mihai Dragos Maliia, Fabrice Bartolomei, Fabienne Picard   +2 more
wiley   +1 more source

The Human Monoacylglycerol Acyltransferase 2 Inhibitor VB‐85387 Is Associated With Weight Loss in Mice With Obesity

Obesity Science & Practice
Background GLP‐1 therapies for obesity are limited by side effects and weight regain is common after treatment ends. Therefore, alternative treatments with new mechanisms are needed for sustained weight loss.
J. Jose Corbalan, Pranavi Jagadeesan, Chia‐Yu Huang, James R. Beasley, Joseph T. Nickels Jr.   +4 more
doaj   +1 more source

Altered cortical synchronization in photosensitive idiopathic generalized epilepsy

Epilepsia, EarlyView.
Abstract Objective To characterize cortical excitability and synchronization dynamics in patients with idiopathic generalized epilepsy (IGE) and photosensitivity by assessing steady‐state visual evoked potentials (SSVEPs) elicited by intermittent photic stimulation.
Alessandro Benedetto, Cecilia Steinwurzel, Francesco Turco, Enrica Bonanni, Roberto Cantello, Gionata Strigaro   +5 more
wiley   +1 more source

Correction to: Laboratory investigation of coupled electrical interaction of fracturing rock with gases

Earth, Planets and Space, 2021
Yuji Enomoto, Tsuneaki Yamabe, Shigeki Sugiura, Hitoshi Kondo   +3 more
doaj   +2 more sources

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Intensive Care Unit Stay and Mechanical Ventilation Among Adults with Respiratory Syncytial Virus-Related Hospitalization by Age and Comorbidity Status

Infectious Diseases and Therapy
Introduction Respiratory syncytial virus (RSV) can cause severe outcomes in hospitalized older adults and those with underlying comorbidities, but little is known regarding such outcomes stratified by age and comorbidity status.
Caihua Liang, Yun Zhou, Matthew Kent, Erica L. Chilson, Bradford D. Gessner, Elizabeth Begier   +5 more
doaj   +1 more source

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

Epilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis, Douglas R. Nordli Jr., Douglas R. Nordli III, Shlomo Shinnar, Stephen Chan, Jacqueline A. Bello, L. Matthew Frank, James Voyvodic, William Gallentine, Syndi Seinfeld, Yoshimi Sogawa, Erica Weiss, David Masur, Yuan Xu, Solomon L. Moshé   +14 more
wiley   +1 more source

VB-84922 is a small molecule that inhibits ER-to-golgi transport of SREBPs-SCAP complexes

Frontiers in Pharmacology
The sterol response element binding proteins (SREBPs), SREBP-1a/c and SREBP-2, are sterol-regulated transcription factors that control the expression of cholesterol and fatty acid-raising genes.
J. Jose Corbalan, Wiebke Schormann, Pranavi Jagadeesan, Justin Kale, Yu-Chiang Huang, Rachael Siegel, James R. Beasley, Jyun-Peng Tung, Axel Nohturfft, David Andrews, Joseph T. Nickels, Joseph T. Nickels   +11 more
doaj   +1 more source

Varia [PDF]

, 2016
Il est des scènes de roman tellement célèbres qu’on a du mal à imaginer qu’elles n’ont pas toujours existé sous cette forme. L’enquête génétique a pour effet, dérangeant mais aussi exaltant, de détruire cette évidence et de nous obliger à regarder d’un ...
Genesis, La rédaction de
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