Results 141 to 150 of about 904,105 (309)
VB-84922 is a small molecule that inhibits ER-to-golgi transport of SREBPs-SCAP complexes
Frontiers in PharmacologyThe sterol response element binding proteins (SREBPs), SREBP-1a/c and SREBP-2, are sterol-regulated transcription factors that control the expression of cholesterol and fatty acid-raising genes.
J. Jose Corbalan +11 more
doaj +1 more source
Geological Journal, EarlyView.Coupled dissolution‐reprecipitation of early formed Cd‐, Fe‐, Ag‐ and Sb‐poor sphalerite through interaction with high‐temperature and high‐sulphur fugacity Cu‐rich fluids, responsible for the formation of the yellow ores, resulted in the formation of Cd‐, Fe‐, Ag‐ and Sb‐rich, heavily chalcopyrite‐diseased sphalerite and enrichment of critical metals ...
Manuel Nopeia +4 more
wiley +1 more source
Orphanet Journal of Rare DiseasesBackground Fabry disease (FD; OMIM # 301500) is a rare, X-linked lysosomal storage disorder caused by mutations in the α-galactosidase A (GLA) gene. Deficiency or absence of alpha-galactosidase A (α-Gal A) enzyme activity leads to the accumulation of ...
Alexandra Dumitriu +9 more
doaj +1 more source
Notable Impact of Paleotectonic Stress on Gold Mineralisation in the West Qinling Orogen
Geological Journal, EarlyView.By applying fuzzy clustering and multiple inverse methods, we systematically processed the data of vein and fault slip in this ore deposit to reveal the transition of orogenic geological environment and paleotectonic stress field. Our research results show two different stress states: the northwest–southeast extensional stress field and the northeast ...
Hongyan Wang +3 more
wiley +1 more source
Leiden Journal of International Law, 2007 This paper argues that the concept of the civilian is a specific way of viewing non-combatants that can be traced to the First World War. Before the war, non-combatants were seen by the law and the prevailing culture as citizens. The citizen was potentially and probably aggressive, bound to the fate of his or her state and, therefore, granted only ...
openaire +2 more sources
Geological Journal, EarlyView.Integrated petrographic, mineralogical and geochemical data from the Hastanetepe Pb–Zn deposit (Balya, Türkiye) reveal multi‐stage hydrothermal alteration and a magmatic sulphur source. Fluid inclusion and sulphur isotope results indicate a complex fluid evolution responsible for skarn‐type Pb–Zn mineralization along limestone–dacite contacts ...
Esra Ünal‐Çakır
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundNumerous bacteria are involved in the etiology of bacterial vaginosis (BV). Yet, current tests only focus on a select few. We therefore designed a new test targeting 22 BV-relevant species.MethodsUsing 946 stored vaginal samples, a new qPCR ...
Ayodeji B. Oyenihi +7 more
doaj +1 more source
Solar and solar-wind oxygen isotopes and the Genesis mission [PDF]
, 2004 The solar oxygen isotope composition is thought to hold important clues to pre-planetary processing of materials in the solar nebula, yet it is essentially unmeasured.
Bochsler, P. +6 more
core
Employee Delight: Conceptualization, Antecedents, and Consequences
Human Resource Development Quarterly, EarlyView.ABSTRACT This article examines the concept of employee delight as a distinct construct within organizational behavior. Based on a systematic literature review, we analyze 10 empirical studies that explicitly address this phenomenon. We propose a multidimensional conceptualization of employee delight as an affective state of highly positive valence and ...
Dalilis Escobar‐Rivera +2 more
wiley +1 more source
The genesis of sudden stratospheric warmings and the quasi-biennial cycles [PDF]
Genesis of sudden stratospheric warmings and quasi-biennial ...
Smith, J. W.
core +1 more source