Results 251 to 260 of about 7,786,025 (339)

Genetic diversity and structure of the red squat lobster (<i>Grimothea monodon</i>) in the Humboldt Current Ecosystem using SNP markers. [PDF]

PeerJ
Quispe-Machaca M, Muñoz-Ramírez C, Brante A, Espinoza P, Zilleruelo M, Torres G, Urzúa Á.   +6 more
europepmc   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Geneticization in the genomic era: a scoping review of ethical, clinical, and sociocultural transformations. [PDF]

Front Sociol
Shaheen S, Ghaly M.
europepmc   +1 more source

A pathway-based genetic score for inflammation: An indicator of vulnerability to phthalate-induced adverse neurodevelopment outcomes

Ahmed Elagali, Alex Eisner, Samuel Tanner, Katherine Drummond, Christos Symeonides, Chloe J. Love, Mimi L.K. Tang, Toby Mansell, David Burgner, Fiona Collier, Peter D. Sly, Martin O’Hely, Sarah A. Dunlop, Peter Vuillermin, Anne‐Louise Ponsonby   +14 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Gene Flooding: Proposal to Flood Invasive Populations With Inbred Individuals as a Form of Low-Tech Genetic Control. [PDF]

Ecol Evol
Gould J, Beranek C.
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Host genetic background and environment have different effects on the establishment and structure of the adult worker honey bee gut microbiota. [PDF]

PLoS One
Stark B, Robinson GE, Vernier CL.
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Reintroduction Without Genetic Bottlenecks: Preserving Diversity in Restored Populations of the Critically Endangered Riverine Shrub <i>Myricaria germanica</i>. [PDF]

Ecol Evol
Iberl K, Reisch C.
europepmc   +1 more source