Results 81 to 90 of about 3,526,863 (119)
Some of the next articles are maybe not open access.
Molecular Genetics and Genetic Variation
2010This chapter contains brief notes on molecular genetics, focusing on those aspects most frequently encountered in genetic epidemiology. The main sections cover the organisation and physical structure of genetic material, the mechanisms involved in transmitting genetic material from one generation to the next, and forms of genetic variation.
M. Dawn Teare, Mohammed-Elfatih Twfieg
openaire +3 more sources
The Genetics of Schizophrenia is the Genetics of Neurodevelopment
British Journal of Psychiatry, 1991Genes are now accepted as being important in the aetiology of schizophrenia (Gottesman & Shields, 1982; McGuffinet al,1987), and over the past decade the emphasis in genetic research has shifted away from genetic epidemiology to searching the chromosomal DNA for the genes themselves. Despite this increasing technical sophistication, the application
Peter B. Jones, Robin M. Murray
openaire +3 more sources
Genetic counselling and the new genetics
Trends in Genetics, 1988Abstract The mapping of most important human disease genes has already been accomplished, promising epochal changes in health care and disease prevention. This article explores the potential benefits and dangers, emphasizing the high priority that must be given to non-directive genetic counselling.
openaire +3 more sources
Current Diabetes Reports, 2003
Adiponectin encoded by the APMI gene is one of the adipocyte-expressed proteins that function in the homeostatic control of glucose, lipid, and energy metabolism. Its dysregulation has been suggested to be involved in disorders covering the metabolic X syndrome, such as insulin resistance, obesity, type 2 diabetes, and coronary artery disease.
Vasseur, F. +3 more
openaire +5 more sources
Adiponectin encoded by the APMI gene is one of the adipocyte-expressed proteins that function in the homeostatic control of glucose, lipid, and energy metabolism. Its dysregulation has been suggested to be involved in disorders covering the metabolic X syndrome, such as insulin resistance, obesity, type 2 diabetes, and coronary artery disease.
Vasseur, F. +3 more
openaire +5 more sources
Current Osteoporosis Reports, 2018
The term osteopetrosis refers to a group of rare skeletal diseases sharing the hallmark of a generalized increase in bone density owing to a defect in bone resorption. Osteopetrosis is clinically and genetically heterogeneous, and a precise molecular classification is relevant for prognosis and treatment. Here, we review recent data on the pathogenesis
Palagano E +3 more
openaire +4 more sources
The term osteopetrosis refers to a group of rare skeletal diseases sharing the hallmark of a generalized increase in bone density owing to a defect in bone resorption. Osteopetrosis is clinically and genetically heterogeneous, and a precise molecular classification is relevant for prognosis and treatment. Here, we review recent data on the pathogenesis
Palagano E +3 more
openaire +4 more sources
Psychiatric Services, 1982
One method of investigating the genetic etiology of alcoholism is to study individuals who were separated soon after birth from their alcoholic biological parents. The author and his colleagues conducted a series of such studies in Denmark; they concluded that, despite little exposure to the alcoholic biological parent, the sons of alcoholics were ...
openaire +6 more sources
One method of investigating the genetic etiology of alcoholism is to study individuals who were separated soon after birth from their alcoholic biological parents. The author and his colleagues conducted a series of such studies in Denmark; they concluded that, despite little exposure to the alcoholic biological parent, the sons of alcoholics were ...
openaire +6 more sources
Genetic imprinting in clinical genetics
Development, 1990ABSTRACT Genetic, and indeed genomic, imprinting does occur in humans. This is manifest at the level of the genome, the individual chromosome, subchromosomal region or fragile site, or the single locus. The best evidence at the single gene level comes from a consideration of familial tumour syndromes.
openaire +3 more sources
Annual Review of Genetics, 1995
Inbreeding depression, accumulation and loss of deleterious mutations, loss of genetic variation in small populations, genetic adaptation to captivity and its effect on reintroduction success, and outbreeding depression are reviewed. The impact of genetic factors in endangerment and extinction has been underestimated in some recent publications ...
openaire +2 more sources
Inbreeding depression, accumulation and loss of deleterious mutations, loss of genetic variation in small populations, genetic adaptation to captivity and its effect on reintroduction success, and outbreeding depression are reviewed. The impact of genetic factors in endangerment and extinction has been underestimated in some recent publications ...
openaire +2 more sources
Genetic testing in prostate cancer management: Considerations informing primary care
Ca-A Cancer Journal for Clinicians, 2022Veda N Giri +2 more
exaly