Results 91 to 100 of about 7,018,639 (311)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego +10 more
wiley +1 more source
Genetic modification and genetic determinism.
Philosophy, ethics, and humanities in medicine : PEHM, 2006 In this article we examine four objections to the genetic modification of human beings: the freedom argument, the giftedness argument, the authenticity argument, and the uniqueness argument. We then demonstrate that each of these arguments against genetic modification assumes a strong version of genetic determinism.
Vorhaus Daniel B, Resnik David B
openaire +3 more sources
Faktor-Faktor yang mempengaruhi kejadian obesitas pada remaja
Jurnal Gizi Klinik Indonesia, 2015 Background: The cause of obesity in adolescents is multifactorial. Increased consumption of fast food (fast food), lack of physical activity, genetic factors, the influence of advertising, psychological factors, socioeconomic status, diet, age, and ...
Weni Kurdanti +6 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason +14 more
wiley +1 more source
Management of Hereditary Spastic Paraplegia: A Systematic Review of the Literature
Frontiers in Neurology, 2019 The term hereditary spastic paraplegia (HSP) embraces a clinically and genetically heterogeneous group of neurodegenerative diseases characterized by progressive spasticity and weakness of the lower limbs.
Marta Bellofatto +4 more
doaj +1 more source
GemTools: A fast and efficient approach to estimating genetic ancestry [PDF]
, 2011 To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on SNP genotypes.
Devlin, Bernie +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich +5 more
wiley +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
New bearings in pharmacotherapeutic strategies: Pharmacogenetics and gene therapy [PDF]
Vojnosanitetski Pregled, 2007 Grbović Leposava +4 more
doaj +1 more source
Diagnosis and treatment of isolated autosomal recessive woolly hair/hypotrichosis
Frontiers in MedicineIsolated autosomal recessive woolly hair/hypotrichosis (ARWH, OMIM:278150) is a rare congenital disorder marked by sparse, tightly curled “woolly” hair.
Ying Xie +13 more
doaj +1 more source