Results 111 to 120 of about 7,018,639 (311)

Differentiable Genetic Programming

open access: yes, 2016
We introduce the use of high order automatic differentiation, implemented via the algebra of truncated Taylor polynomials, in genetic programming. Using the Cartesian Genetic Programming encoding we obtain a high-order Taylor representation of the ...
Biscani, Francesco   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Absence of the LRRK2 mutation in Emirati Parkinson’s disease patients in contrast to other Arab populations

open access: yesFrontiers in Aging Neuroscience
BackgroundThe role of genetic factors in the pathogenesis of Parkinson’s disease (PD) is characterized by heterogeneity in specific genetic variations and their prevalence across different populations and geographic locations.ObjectiveTo investigate the ...
Vinod Metta   +11 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

GSE’s 50th anniversary: where do we go from now?

open access: yesGenetics Selection Evolution, 2019
Genetic Selection Evolution’s Editorial Board
doaj   +1 more source

A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young

open access: yesJACC: Advances
Background: Thoracic aortic dissection (TAD) causing sudden cardiac death (SCD) in the young is overlooked and poorly described. Objectives: The purpose of this study was to assess: 1) the incidence of TAD-related SCD, and 2) the prevalence and features ...
Monica De Gaspari, MD, PhD   +14 more
doaj   +1 more source

IBPGR: The Strategy [PDF]

open access: yes, 1988
Strategy paper approved by the IBPGR Board, articulating the strategies and objectives for carrying out the new and expanded mandate approved by the CGIAR in the wake of IBPGR's 1986 external review.
International Board for Plant Genetic Resources
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

In memoriam

open access: yesGenetics & Applications, 2019
Institute for Genetic Engineering and Biotechnology
doaj   +1 more source

Structural brain MRI abnormalities in SCN1A-, SCN2A-, SCN3A-, and SCN8A-related epilepsies: a cohort study

open access: yesFrontiers in Neurology
PurposeTo characterize the prevalence and patterns of structural brain magnetic resonance imaging (MRI) abnormalities in children with genetically confirmed SCN1A-, SCN2A-, SCN3A-, or SCN8A-related epilepsy and to identify genotype-specific imaging ...
Daewoong Ahn   +13 more
doaj   +1 more source

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