Results 111 to 120 of about 232,851 (305)
Two rare mutations in homozygosity synergize to silence TREX1 in Aicardi-Goutières syndrome
Frontiers in ImmunologyBackgroundAicardi-Goutières syndrome (AGS) is a rare monogenic type I interferonopathy characterized by dysregulated inflammation and tissue damage that primarily affects the central nervous system.
Tamar Rubin +15 more
doaj +1 more source
Variability, heritability and genetic advance in sugarcane (Saccharum spp. hybrid) genotypes
, 2023 The study was carried out with the aim of estimating variability, heritability, and genetic advance for 196 sugarcane genotypes. Results of the analysis of variance identified a very highly significant variation among the genotypes in all the traits ...
Belay Tolera (15308570) +2 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
SGRP annual report 2004/2005: Of the CGIAR System-wide Genetic Resources Programme
, 2019 SGRP seeks to improve the effectiveness of the CGIAR System in managing genetic resources as global public goods, including the delivery of research, knowledge and capacity-development.
CGIAR Systemwide Genetic Resources Programme
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Genetic diversity of mango (Mangifera indica) bioactive components
The Indian Journal of Agricultural Sciences, 2019 The move towards fruit with high concentration of specific nutritional components will help the breeders to select appropriate genotypes which can be used as key drivers in nutritional breeding.
G L VEENA, B M MURALIDHARA, S RAJAN
doaj +1 more source
Studies of genetic variability, heritability and genetic advance in balsam (Impatiens balsamina L.)
, 2018 A field experiment was carried out with 34 genotypes of Balsam (Impatiens balsamina L.) to assess the variability, heritability and genetic advance with an objective to identify superior genotypes for further crop improvement programme.
Pal, Sumit +9 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Electronic Journal of Plant Breeding, 2019 The success of crop improvement programme depends on the extent of genetic variability existing in the population of germplasm. The improvement and development of new varieties depends to a great extent upon the magnitude of genetic variability.
M. A. Patel +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source