Results 121 to 130 of about 232,851 (305)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
, 2018 Genetic variability, heritabality and genetic advance studies showed high range for number of flower per plant (19.57-44.10) and fresh weight of flower (2.94-16.89 g). The co-efficient of variation (PCV and GCV) was maximum for number of flower per plant
AND V. S. PATIL, V. P. DEEPA
core
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Genetic variability, heritability and genetic advance studies in topcross and three-way cross maize (Zea mays L) hybrids [PDF]
, 2016 Understanding the genetic variability, heritability and genetic advance of traits in any plant population is an important pre-requisite for selection program.
Ariyo, O.J. +3 more
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FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Variability for dry fodder yield and component traits in cowpea [Vigna unguiculata (L.) Walp] [PDF]
Electronic Journal of Plant Breeding, 2014 Eleven cowpea genotypes were evaluated and significant genotypic effects for most of the traits studied. Number of pods/plants, pod, seed and dry fodder yields were high for phenotypic and genotypic coefficients of variation.
Olayiwola M.O. 1and P.A.S. Soremi2
doaj
Report of the Third Meeting of the CGIAR Genetic Resources Policy Committee
, 1996 A summary report of the major conclusions of the third meeting of the CGIAR Genetic Resources Policy Committee held in Rolle, Switzerland in February 1996, prepared by Chairman M. S. Swaminathan and distributed in advance of MTM96.
Swaminathan, M.S. +1 more
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source