Results 151 to 160 of about 232,851 (305)

Assessment of genetic variability, heritability and genetic advance in brinjal (Solanum melongena L.)

Brinjal breeding lines of the F3 population (IC0598430 X CARI 1) were evaluated to estimate variability, heritability and genetic advance for different characters.
Naresh, Ponnam, Tripathy, Pradyumna, Vasa, Anil Kumar, Singh, Gowtham, Adamala, Anil Reddy, Sahu, Gouri Shankar, Acharya, Gobinda Chandra, Koundinya, AVV, Petikam, Srinivas   +8 more
core   +1 more source

Variablity, heritability and genetic advance in quantitative traits of Tef [Eragrostis Tef (ZUCC.) Trotter]: implication for genetic improvement strategies

, 2013
Seventy nine tef populations collected from ten administrative regions and seven altitude classes were planted with two improved varieties in simple lattice design at Gute and Bako during 2007 and 2008 cropping season, respectively, to assess variability,
Bekele, Endashaw, Lule, Dagnachew, Ayana, Amsalu   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Phenotypic Evaluation of Genetic Diversity of Diverse Indian Mustard (Brassica Juncea L. Czern and Coss) Genotypes using Correlation and Path Analysis

International Journal of Bio-Resource and Stress Management, 2019
The present investigation was undertaken at experimental field, department of plant breeding and genetics, Sher-e-Kashmir University of Agricultural Sciences and Technology, Jammu, Jammu & Kashmir state, India for phenotypic evaluation of genetic ...
Lekhraj Jat, S. K. Rai, Jeet Ram Choudhary, Vanya Bawa, Richa Bharti, Mridhu Sharma, Madhavi Sharma   +6 more
doaj  

Genetic Variability, Heritability, Genetic Advance and Trait Associations in Selected Sorghum (Sorghum Bicolor L. Moench) Accessions in Ethiopia

, 2020
Genetic variability can be defined as the genetic makeup of organisms within a population change. The objective of this study aims to analyze and determine the traits having greater interrelationship with grain yield utilizing the correlation and path ...
Senbetay, Tsegau
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Genetic variability, heritability and genetic advance studies in top- cross and three-way cross maize (Zea mays L) hybrids

, 2018
Understanding the genetic variability, heritability and genetic advance of traits in any plant population is an im- portant pre-requisite for selection program.
Ariyo, Omolayo J, Sesay, Sayo, Ojo, David K, Meseka, Silvestro   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source