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Integrating genomic insights and artificial intelligence to elucidate lipoprotein(a)-mediated risk in cardio-renal syndrome. [PDF]
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Nature Reviews Gastroenterology & Hepatology, 2014
IBD is a spectrum of chronic disorders that constitute an important health problem worldwide. The hunt for genetic determinants of disease onset and course has culminated in the Immunochip project, which has identified >160 loci containing IBD susceptibility genes.
Van Limbergen, Johan +2 more
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IBD is a spectrum of chronic disorders that constitute an important health problem worldwide. The hunt for genetic determinants of disease onset and course has culminated in the Immunochip project, which has identified >160 loci containing IBD susceptibility genes.
Van Limbergen, Johan +2 more
openaire +3 more sources
Advances in molecular genetics
The American Journal of Surgery, 1997The three known mechanisms of cellular transformation and oncogenesis include mutations in proto-oncogenes, inactivation of both copies of a tumor suppressor gene, and defects in DNA mismatch repair genes. Examples of each are included to substantiate the importance of understanding these mechanisms.
T C, Lairmore, J A, Norton
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Current Opinion in Rheumatology, 2013
The purpose of this review is to highlight recent progress in defining the effects of variation in the germline DNA sequence on the susceptibility to systemic lupus erythematosus.The genetic contributions to lupus susceptibility have been increasingly defined in recent years, although a large proportion of the genetic heritability of this disease ...
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The purpose of this review is to highlight recent progress in defining the effects of variation in the germline DNA sequence on the susceptibility to systemic lupus erythematosus.The genetic contributions to lupus susceptibility have been increasingly defined in recent years, although a large proportion of the genetic heritability of this disease ...
openaire +2 more sources

