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Advances in HLA Genetics

2015
The major histocompatibility complex (MHC) is a genetic system of over 70 known genes that occupies the midportion of the short arm of the sixth chromosome (C6p) and spans about 4 million base pairs of DNA. The high-resolution typing of class I and class II MHC genes and the identification of genes between and near them has increased the definition of ...
D, Corzo   +3 more
openaire   +2 more sources

Advances in glaucoma genetics

2015
Glaucoma is presumed to be a complex progressive neurodegenerative disorder caused by genetic and environmental factors, and it is also one of the leading causes of irreversible blindness worldwide. Glaucoma is divided into two major forms: primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG).
Yoichi, Sakurada, Fumihiko, Mabuchi
openaire   +2 more sources

Advances in genetic diagnosis

Current Opinion in Pediatrics, 1993
For many years, the mainstay of pediatric genetic testing was chromosomal analysis. Based on a technology developed in the 1950s and refined in the 1960s, this approach permitted the detection of abnormalities of chromosome number and some structural rearrangements.
openaire   +2 more sources

Advances in genetic hypertension

Current Opinion in Pediatrics, 2007
Mendelian forms of hypertension are rare genetic disorders that cause severe hypertension. This review will explore the recently identified molecular mechanisms and pathogenesis of genetic disorders that cause hypertension in children.Hypertension is now believed to be a polygenic disorder resulting from the interaction of multiple genes and the ...
openaire   +2 more sources

Genetic Advance in Depressive Disorder

2019
Major depressive disorder (MDD) and bipolar disorder (BPD) are both chronic, severe mood disorder with high misdiagnosis rate, leading to substantial health and economic burdens to patients around the world. There is a high misdiagnosis rate of bipolar depression (BD) just based on symptomology in depressed patients whose previous manic or mixed ...
Chen, Zhang, Han, Rong
openaire   +2 more sources

Genetic testing in prostate cancer management: Considerations informing primary care

Ca-A Cancer Journal for Clinicians, 2022
Veda N Giri   +2 more
exaly  

Genetic variation and genetic advance in cowpea based on yield and yield-related traits

Acta Agriculturae Scandinavica - Section B Soil and Plant Science, 2020
Jacob Mashilo, Hussein Shimelis
exaly  

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