Results 81 to 90 of about 2,781,392 (308)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Genetic variability for yield and yield attributing traits in F4 generation of Lablab bean (Lablab purpureus L. Sweet)

open access: yesElectronic Journal of Plant Breeding, 2016
Ninety one progenies from F4 generation along with one check of Lablab bean were evaluated to study the genetic variability for yield and yield attributing traits.
S.S. Kambale   +4 more
doaj   +1 more source

Study of genetic variability, heritability, and genetic advance for yield-related traits in tomato (Solanum lycopersicon MILL.). [PDF]

open access: yesFront Genet, 2022
Rasheed A   +10 more
europepmc   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Genetic Variability for Quantitative Traits in China Aster [Callistephus chinensis (L.) Nees]

open access: yesJournal of Horticultural Sciences, 2014
A field study was conducted to estimate genetic variability, heritability and genetic advance in 20 genotypes of China aster for 15 traits during the year 2012-13 in Randomized Complete Block Design, with three replications.
Gayatri Khangjarakpam   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

A survey of genetic improvement search spaces [PDF]

open access: yes, 2019
Genetic Improvement (GI) uses automated search to improve existing software. Most GI work has focused on empirical studies that successfully apply GI to improve software's running time, fix bugs, add new features, etc. There has been little research into
Alexander, B   +17 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Two rare mutations in homozygosity synergize to silence TREX1 in Aicardi-Goutières syndrome

open access: yesFrontiers in Immunology
BackgroundAicardi-Goutières syndrome (AGS) is a rare monogenic type I interferonopathy characterized by dysregulated inflammation and tissue damage that primarily affects the central nervous system.
Tamar Rubin   +15 more
doaj   +1 more source

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