Results 211 to 220 of about 63,933,562 (254)

Elastic parametric response mapping: quantitative CT scoring for local COPD severity. [PDF]

Thorax
Labaki WW, Ram S, Namvar A, Bell AJ, Hoff BA, Kazerooni EA, Galban S, Martinez FJ, Hatt CR, Murray S, Mirkes EM, Gorban AN, Zinovyev A, Han MK, Galban CJ.   +14 more
europepmc   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa. [PDF]

J Inherit Metab Dis
Mitchell JJ, Abdenur JE, de Boer F, Boyer M, Breilyn MS, Couce ML, De Leon DD, Derks TG, El-Gharbawy A, Haijer-Schreuder AB, Loechner K, Longo N, Lund AM, Olmos MAM, McCandless SE, de Oliveira BM, Mount M, Muschol N, Pytlak K, Radhakrishnan K, Riba-Wolman R, Rodriguez-Buritica DF, La Rosa A, Rossi A, Saavedra H, Santer R, Shayota B, Smit GPA, Moura De Souza CF, van der Klauw MM, Weinstein DA, Wolfsdorf JI, Blake A, Grimm AA, Mitragotri D, Rahman S, Turner-Bowker DM, Collis R.   +37 more
europepmc   +1 more source

Modeling Progressive Brain Volume Losses in Chronic Moderate Severe Traumatic Brain Injury: Extensive, but Attenuating

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive brain atrophy has now been widely observed in the chronic stages of moderate–severe traumatic brain injury (msTBI), but there is only coarse information regarding its prevalence and magnitude, and whether rate of atrophy accelerates or attenuates across time. We examined these questions in a Canadian inception cohort from
Robin E. A. Green, Brenda Colella, Alana Changoor, David J. Mikulis, Adrienne Li, Kadeen Johns, Georges A. Monette   +6 more
wiley   +1 more source

Family SES amplifies genetic influences on organized activity involvement from childhood to young adulthood: evidence from the German twin family panel. [PDF]

Front Sociol
Liu Y.
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway-Related Obesity: Vision & Evidence. [PDF]

Clin Obes
Argente J, van den Akker ELT, Cetiner M, Clément K, Forsythe E, Garfield A, Kühnen P, Martos-Moreno GÁ, Meeker D, Müller HL, van Santen HM, von Schnurbein J, Segrestin B, Tanaka T, Tena-Sempere M, Wabitsch M, Zorn S, Farooqi IS.   +17 more
europepmc   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella, Veria Vacchiano, Vittorio Velucci, Stefano Zoccolella, Rocco Liguori, Giovanni Defazio   +5 more
wiley   +1 more source