Results 1 to 10 of about 12,171 (220)
Ring-Opening Polymerization of ε-Caprolactone Initiated by Ganciclovir (GCV) for the Preparation of GCV-Tagged Polymeric Micelles [PDF]
Molecules, 2015 Ganciclovir (GCV) is a nucleoside analogue with antiviral activity against herpes viral infections, and the most widely used antiviral to treat cytomegalovirus infections.
Alicia J. Sawdon, Ching-An Peng
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Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells [PDF]
The Scientific World Journal, 2013 Although the combination of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) with ganciclovir (GCV) has been shown as a promising suicide gene treatment strategy for glioma, the almost immunodepressive dose of GCV required for its adequate in ...
Lei-qing Li +5 more
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Hepatoma-Targeted Radionuclide Immune Albumin Nanospheres: 131I-antiAFPMcAb-GCV-BSA-NPs [PDF]
Analytical Cellular Pathology, 2016 An effective strategy has been developed for synthesis of radionuclide immune albumin nanospheres (131I-antiAFPMcAb-GCV-BSA-NPs). In vitro as well as in vivo targeting of 131I-antiAFPMcAb-GCV-BSA-NPs to AFP-positive hepatoma was examined.
Mei Lin +8 more
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Renal maturation and catch-up clearance of ganciclovir in a preterm neonate: Bayesian pharmacokinetic analysis using a population model [PDF]
Journal of Pharmaceutical Health Care and SciencesBackground Congenital cytomegalovirus (CMV) infection is a major cause of neonatal morbidity. However, optimizing ganciclovir (GCV) dosing in preterm infants is complicated by immature renal function and developmental pharmacokinetics.
Katsuya Kata +6 more
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HSV-TK/GCV 系统治疗口腔鳞癌移植瘤的研究 [PDF]
Zhongshan Daxue xuebao. Yixue kexue ban, 2002 【目的】探讨腺病毒介导单纯疱疹病毒胸苷激酶基因(AdCMVHSV-TK)/ 丙氧鸟苷(GCV)自杀基因系统对口腔 鳞癌移植瘤的治疗作用。【方法】Tca8113 细胞接种于裸鼠右侧腋下, 移植瘤形成时随机分成4 组:①空白对照组, ②Ad- CMVHSV-TK 对照组(2×109 PFU, 瘤内注射), ③GCV 对照组(25 mg/ kg , Bid ×6, 腹腔注射), ④AdCM VHSV-TK/ GCV 治疗 组, 并开始治疗。观察肿瘤的生长状态、计算抑瘤率和肿瘤群体倍增时间 ...
黄洪章, 王安训, 李 苏
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Morphometric Analysis of Great Cardiac Vein and its Clinical Implication-A Cadaveric Study [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Great Cardiac Vein (GCV) is the longest venous vessel of heart. It is the main tributary of the coronary sinus and anterior wall of the left ventricle and interventricular septum are drained by GCV. Aim: To study the morphometry of GCV and
Jolly Agarwal +3 more
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Frontiers in Pharmacology, 2022 Ganciclovir (GCV) is a prodrug nucleoside analogue and is clinically used as antiviral drug for the treatment of cytomegalovirus (CMV) and other infections.
Lin-Kong Gong +11 more
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Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies
Genome Medicine, 2022 Background Ganciclovir (GCV) is widely used in solid organ and haematopoietic stem cell transplant patients for prophylaxis and treatment of cytomegalovirus. It has long been considered a mutagen and carcinogen. However, the contribution of GCV to cancer
Hu Fang +20 more
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Barekeng, 2021 Penelitian ini menggunakan model regresi nonparametrik birespon dengan pendekatan spline truncated. Model tersebut digunakan untuk menyelesaikan permasalahan analisis regresi yang bentuk kurvanya tidak diketahui.
Aprianti Boma Padatuan +2 more
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Barekeng, 2023 The nonparametric regression approach is used when the shape of the regression curve is not known. The advantage of nonparametric regression is that it has a high degree of flexibility.
Sitti Anggraeni +2 more
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